Conclusion FHIT gene may play a role in the regulation of cell proliferation of lung cancer, and the reduction in FHIT expression may be related to the pathogenesis of lung cancer.
结论FHIT基因可能参与肿瘤细胞增殖的调控，FHIT基因表达下降可能与肺癌的发生密切相关。
There exist hypermethylation, abnormal transcription of FHIT gene and down-regulation expression of FHIT protein in liver cancer.
肝癌中存在FHIT基因高甲基化、转录异常、FHIT蛋白表达下降。
FHIT is an important tumor suppressor gene, in a variety of tumors expression was found missing.
FHIT是一种重要的抑癌基因，在多种肿瘤中被发现表达缺失。
To investigate the expression of apoptosis inhibitor gene FHIT in human glioma and study its clinical-pathological implication and clinical significance.
目的探讨人脑胶质瘤组织脆性组胺三联体(FH IT)的表达及其临床意义。
Conlusion The human FHIT recombinant eukaryotic expression plasmid was constructed successfully.
结论成功构建了重组人FHIT真核表达质粒。
The expression level of FHIT gene was closely related to histological classification, cancer cell differentiation, P TNM stages and lymph node involvement in lung cancer patients (P<0.05).
肺癌组织中FHIT基因表达水平降低与肺癌组织学类型、细胞分化程度，患者PTNM分期、淋巴结转移程度存在相关性（P< 0 .0 5） ；
Objective: To investigate the expression characteristics of FHIT protEin in breast carcinomas and its relationship with clinicopathological parameters.
目的：探讨FHIT基因蛋白在乳腺癌中的表达特点及其与临床病理参数的关系。
Methods: Matched normal and cancerous tissues from 41 patients with colorectal cancer and 25 patients with colorectal adenoma were examined for FHIT expression using RT-PCR.
方法：采用逆转录巢式酶链免疫反应，对41例结直肠癌组织及其配对的癌旁正常组织和25例良性腺瘤的FHIT基因进行检测。
Objective To study the expression of fragile histidine triad (FHIT) in oral squamous cell carcinoma (OSCC), and discuss its role and significance in OSCC.
目的：检测抑癌基因脆性组氨酸三聚体(FHIT)基因在口腔鳞状细胞癌(OSCC)的表达情况，探讨其在OSCC发生过程中的作用及其意义。
The loss of FHIT expression did not correlate with histological type, cell differentiation, clinical stage and metastasis, but was frequently observed in tobacco smokers.
FHIT基因失活与吸烟相关，但与组织学类型、分化程度、临床分期和转移无关。
Abnormalities in the FHIT gene its expression have been identified in a variety of human cancer cell lines and tumors.
越来越多的研究发现FHIT基因在大量的原发性肿瘤及细胞株中存在异常，该基因被认为是一个候选的抑癌基因。
Methods: Expression of FHIT protEIn in breast carcinoma tissues of 62 cases was detected by SP immunohistochemistry.
方法：采用免疫组织化学sp法，检测62例乳腺癌组织中FHIT蛋白的表达情况。
Methods: Expression of FHIT protEIn in breast carcinoma tissues of 62 cases was detected by SP immunohistochemistry.
方法：采用免疫组织化学sp法，检测62例乳腺癌组织中FHIT蛋白的表达情况。
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