In most other human tissues, FASN is minimally expressed since they rely on circulating fatty acids for new structural lipid synthesis (18).
在大多数别的人类组织中,FASN表达量很低,因为它们依赖于循环脂肪酸形成新的脂肪(18)。
A recent identification of cross-talk between FASN and well-established cancer-controlling networks begins to delineate the oncogenic nature of FASN-driven lipogenesis.
目前一项鉴定研究FASN与构建良好的肿瘤控制网络的工作已开始描述揭示FASN驱使的脂肪生成的致癌本质。
Background: Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN.
背景:脂肪酸合成酶(FASN)过表达参与了前列腺癌的发生。我们直接研究FASN的致癌潜能。
FASN is active as a homodimer with seven different catalytic activities and produces lipids in the liver for export to metabolically active tissues or storage in adipose tissue.
FASN是一种活化的同二聚体具有七种不同的催化活性,在肝脏中产生脂肪以运输进入代谢活跃的组织或储存在脂肪组织中。
FASN is active as a homodimer with seven different catalytic activities and produces lipids in the liver for export to metabolically active tissues or storage in adipose tissue.
FASN是一种活化的同二聚体具有七种不同的催化活性,在肝脏中产生脂肪以运输进入代谢活跃的组织或储存在脂肪组织中。
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