Scientists have known that the protein complex known as FANCI-FANCD2 responds to DNA damage and repairs cross-linking, but the details of how the complex works have been unknown.
科学家早已确信存在一种称为FANCI-FANCD2的蛋白复合物,该复合体与DNA损伤及交联修复有并,至于其作用机制尚未可知。
Beyond these details, the researchers knew that repair involves snipping out and replacing the damaged DNA, but didn't know if FANCI and FANCD2 play a role in this molecular tailoring.
除了这些细节,研究者还了解,修复过程包括修剪和替换损坏的DNA,但是不了解FANCI和FANCD 2是否在分子裁剪过程中起作用。
Beyond these details, the researchers knew that repair involves snipping out and replacing the damaged DNA, but didn't know if FANCI and FANCD2 play a role in this molecular tailoring.
除了这些细节,研究者还了解,修复过程包括修剪和替换损坏的DNA,但是不了解FANCI和FANCD 2是否在分子裁剪过程中起作用。
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