The team showed only those cells with EZH2 phosphorylated by CDK1 differentiated into bone cells.
本研究小组显示只有那些携带被CD K 1磷酸化了的EZH2的细胞才会分化为骨细胞。
The MDS patients with DNA methylation had higher EZH2 expression than those without DNA methylation.
发生DNA甲基化的MDS患者EZH2表达水平高于未发生DNA甲基化的患者。
We then detected EZH2 protein expression in the esophageal squamous carcinoma, paracarcinomatous and normal tissues by Western blotting.
方法 采用免疫组织化学染色法、免疫印迹法,分析检测食管癌标本中EZH2蛋白的表达。
Results The immunohistochemical staining showed EZH2 protein was highly expressed in esophageal squamous carcinoma and adenocarcinoma tissues.
结果食管癌组织标本均高表达EZH2蛋白,阳性染色定位于细胞核;
In a series of experiments, the team demonstrated how CDK1 interferes with EZH2, reducing cell migration and invasion in breast cancer cell lines.
该团队以系列的实验证实了CDK1干扰EZH2的具体过程,这种干扰减少了乳腺癌细胞系中的细胞迁移与浸润。
The team's basic research findings provide a rationale for developing an EZH2 inhibitor or a drug that mimics the protein that deactivates it as new cancer drugs.
该团队的初步研究发现为开发EZH2酶抑制剂或开发一种新的抗癌药物(模仿使该酶失活的蛋白)提供了合理的依据。
Objective To investigate the expressions of EZH2 protein in the human immortalized esophageal epithelial cell line (SHEE) and the malignant transformation cell line (SHEEC).
目的研究EZH2蛋白在食管上皮永生化细胞系(SHEE)和恶性转化细胞系(SHEEC)中的表达。
Objective To investigate the expressions of EZH2 protein in the human immortalized esophageal epithelial cell line (SHEE) and the malignant transformation cell line (SHEEC).
目的研究EZH2蛋白在食管上皮永生化细胞系(SHEE)和恶性转化细胞系(SHEEC)中的表达。
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