"It's a work in progress, but we believe that the expression of genes in the brain and how they are regulated is at least an indicator of how well someone is aging," Yankner says.
这项工作还未结束,但我们认为,大脑中的基因表达及调控——至少是研究个体老化的一个指针。
Gene expression in eukaryotes is regulated primarily at the level of transcription.
在真核生物中基因表达的调节主要是在转录水平。
Gene expression is regulated by the complex interaction of many cis-acting elements and trans-acting factors.
基因表达是由众多顺式作用元件和反式作用因子相互作用调控的。
This function is accomplished through activating the PKC, and the expression of CD133 is regulated possibly after transcription.
这一作用主要通过活化蛋白激酶C(PKC)通路来实现,而CD133抗原表达可能是转录后进行调节。
Holds that currently used drawing expression methods need to be regulated and unified to improve design and raise efficiency.
指出暖通空调施工图绘图表示方法迫切需要规范统一,以提高设计效率和设计质量。
Objective: To investigate the expression of extracellular signal regulated protein kinase(ERK) signal transduction pathway and its significance in the rat brain after epileptic seizures.
目的:研究细胞外信号调节蛋白激酶(ERK)信号通路在癫痫大鼠脑内的表达规律及其意义。
Promoters are important elements that regulated gene expression, activity of promoters indirectly reflect gene expression that they control.
启动子是基因表达调控的重要元件,启动子的活性间接反映了它所控制的基因的表达。
Objective To investigate the expression of the glucose regulated protein (GRP78, GRP94) in rats during focal cerebral ischemia.
目的研究大鼠局灶性脑缺血时糖调控蛋白(GRP78、GRP94)的表达。
Their expression is developmentally regulated and stage specific.
它们的表达是受发育调节的和有阶段特异的。
Aldosterone secretion is regulated largely at the level of expression of the final enzyme required for its biosynthesis, aldosterone synthase (CYP11B2).
醛固酮合酶(CYP11B2)是醛固酮生物合成最后一步的催化酶。醛固酮的分泌主要由醛固酮合酶的表达水平来调节。
Changes of telomere structure, length and expression of telomerase are regulated by a complex network of many associated proteins.
端粒的结构和长度变化、端粒酶的表达水平在众多相关蛋白所组成的复杂调控网络的作用下保持平衡。
A regulated gene expression system would offer the unique opportunity to study the gene physiological functions at different developmental stages.
如果获得一种可以特异调控基因表达的系统,对于研究某一基因在各个不同发育时期的功能会有很大的帮助。
Conclusion the up-regulated expression of MIF can make the increase of macrophages and natural killer cells, it is one of the reasons of tumor development.
结论:卵巢癌组织中MIF蛋白表达上调导致巨噬细胞和自然杀伤细胞增多,可能是肿瘤进一步恶化的原因之一。
To investigate the expression of extracellular signal-regulated kinase (ERK) and its significance in epithelial ovarian tumor.
探讨细胞外信号调节激酶(ERK)在卵巢上皮性肿瘤组织中的表达及其意义。
CONCLUSION: Hypercholesterolemia altered the vascular functions and regulated gene expression levels of specific inward rectifier and ATP-sensitive potassium channel subtypes.
结论:高胆固醇血症可改变血管功能,并影响某些内向整流和AT P敏感钾通道亚型的基因表达。
Objective:To study apoptosis of glial cells and expression of proteins of apoptotic regulated genes in white matter after spinal cord transection in rats.
目的:研究大鼠脊髓横断后白质内胶质细胞凋亡改变以及凋亡相关基因产物表达情况。
Several techniques have been employed to identify the gene whose expression is differentially regulated in response to various environmental stresses in higher plants.
目前,几种分子生物学技术已用于克隆鉴定多种环境胁迫下的差异表达基因。
The expression of heat shock protein genes in eukaryotes is regulated by heat shock transcription factor (HSF).
真核生物中热激蛋白基因的表达受热激转录因子的调节。
Conclusion the up-regulated expression of MCP-1 and RANTES in transplant kidney tissue may play a role in the pathogenesis of chronic allograft nephropathy.
结论肾组织中MCP 1和RANTES的表达升高可能与慢性移植肾肾病的发生有关。
In plants, the expression of many genes is regulated at transcriptional level, and mostly by cis - and trans-acting elements.
许多植物基因表达的调控发生在转录水平上,主要受顺式元件和反式因子的调控。
Gene expression is regulated at different levels.
基因表达受不同层次的调控。
The adaptation of plants to water stress is regulated by the ABA-dependent gene expression pathway and the ABA-independent gene expression pathway.
植物在水分胁迫条件下以依赖aba和不依赖aba的基因表达途径来调节对逆境的适应。
It is obviously down-regulated in nasopharyngeal carcinoma (NPC) cells and tissues. Over expression of BRD7 in NPC cells can inhibit cell proliferation and cell cycle progression.
它在鼻咽癌细胞和组织中表达明显下调,过表达BRD7基因可抑制鼻咽癌细胞的生长和细胞周期的进程。
Objective Discussing the relationship between the PS2 estrogen-regulated protein expression in breast cancer and clinical pathology.
目的探讨雌激素调节蛋白ps 2在乳腺癌中的表达及其临床病理间的关系。
Results IL 6 up regulated the expression of CD14 and down regulated the expression of SR in a time and dose dependent fashion at the level of mRNA.
结果在基因转录水平,IL6对CD14表达呈时间剂量依赖性上调,对SR的表达呈进行性下调;
The up-regulated expression of these genes might be closely related to the DM trait.
因此,这几个基因的上调表达很可能与双肌臀性状的发生关系密切。
Results The expression of NMDAR1 in lumbar DRGs was dramatically down-regulated after sciatic nerve section.
结果坐骨神经切断后大鼠腰段背根节内NMDAR1的表达显著下调。
Results The expression of NMDAR1 in lumbar DRGs was dramatically down-regulated after sciatic nerve section.
结果坐骨神经切断后大鼠腰段背根节内NMDAR1的表达显著下调。
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