Expression of an oncogene in a primary cell can, paradoxically, block proliferation by inducing senescence or apoptosis through pathways that remain to be elucidated.
初始细胞的癌基因的表达往往会通过诱导细胞凋亡、衰老来阻止细胞的增值的,而其实现上述功能的具体途径仍有待澄清。
Conclusions High DR expression is prevalent in anaplastic astrocytoma tissue and this may contribute to the apoptosis-inducing therapy of anaplastic astrocytoma.
结论间变性星形细胞瘤细胞中普遍存在DR的高表达,这可能为间变性星形细胞瘤的凋亡诱导治疗提供新的靶点。
SIR is relative to inducing and expression of some of cytokines such as ET and TNF .
全身炎症反应与一些细胞因子如内皮素、肿瘤坏死因子等的诱导表达有关。
Aim This study was designed to explore the differential proteomic expression inducing effect of diallyl disulfide (DADS) on human colonic cancer SW480 cells and its related molecular mechanisms.
该实验旨在研究二烯丙基二硫(DADS)体外诱导人结肠癌s W 480细胞蛋白质组差异表达的相关分子机制。
High death receptor expression may play an important role in TRAIL inducing pancreatic carcinoma apoptosis.
死亡受体在胰腺癌中高表达,可能在TRAIL诱导胰腺癌细胞凋亡的机制中发挥重要的作用。
Aim: to investigate the relationship between the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), cell proliferation and apoptosis in children's skin hemangioma.
目的探讨小儿皮肤血管瘤各阶段肿瘤坏死因子相关凋亡诱导配体(TRAIL)的表达与细胞增殖和凋亡的关系。
The meaning of ISE was defined; the complexity of fertility expression of PTGMS lines, the drift of critical sterility inducing tempera tu.
光温敏不育系不育性表达不稳定是近年来两系杂交水稻研究和应用中遇到的一大难题。
Objective to investigate the correlation between sensitivity to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and expression level of death receptor 5 (DR5) on tumor cell surface.
目的探讨肿瘤细胞表面dr5表达水平与其对肿瘤坏死因子相关的凋亡诱导配体(TRAIL)敏感性之间的关系。
Objective To screen out genes associated with malignant progression of glioma, based on the established glioma cell differentiation-inducing gene expression profiles.
目的利用已经建立的胶质瘤细胞诱导分化相关基因表达谱,筛选胶质瘤恶性进展相关基因。
The main anticancer mechanisms of Tetrandrine were inducing tumor cells apoptosis, down-regulating the expression of MRP.
其作用机制与诱导肿瘤细胞凋亡,下调MRP表达等有关。
Conclusion Long-term estrogen replacement treatment might protect cardiovascular system through decreasing the blood pressure and inducing the expression of IRS-1 in myocardium.
结论:长期雌激素替代治疗可降低血压、增加心肌细胞IRS 1的表达,从而一定程度上保护心血管。
Objective Establishment of a gene expression profile associated with differentiation inducing the glioma cells was made possible.
目的建立胶质瘤诱导分化相关基因表达谱。
Results PAR-2 was weakly expressed in cytoplasm and membrane before SAP was induced, and the expression increased after inducing of SAP.
结果 正常胰腺组织胞浆及胞膜弱表达PAR-2,造模后表达升高。
Results PAR-2 was weakly expressed in cytoplasm and membrane before SAP was induced, and the expression increased after inducing of SAP.
结果 正常胰腺组织胞浆及胞膜弱表达PAR-2,造模后表达升高。
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