Objective To explore the mechanism of evodiamine in treating Carcinoma.
目的探讨吴茱萸碱抗肿瘤的作用机制。
Evodiamine can be desorped by 90% alcohol, but Rutaecarpin almost can't.
乙醇对吴茱萸碱洗脱能力较强而对吴茱萸次碱则较弱；
Objective To study the mechanism of L929 cell death induced by Evodiamine in vitro.
目的研究吴茱萸碱体外诱导l 929细胞死亡的机制。
METHODS: Evodiamine and rutaecarpine were extracted with the solvent ethyl acetate and the ultrasonic extractor.
方法：以乙酸乙酯为溶剂用超声震荡提取法提取吴茱萸碱和吴茱萸次碱。
Conclusion: Evodiamine could inhibit invasion of human gastric carcinoma cell through down regulating of PLK1 expression.
结论：吴茱萸碱可明显抑制胃癌细胞侵袭力，其机制可能与下调PLK1基因表达有关。
AIM: to compare the cytotoxic effect of evodiamine with chemotherapy drugs on A375-S2 cells, and to examine the relationship between the effects of PKC and ERK on evodiamine-induced cell death.
目的：对比吴茱萸碱与化疗药物对A375 - S2细胞的细胞毒活性，并且研究PKC及ERK激酶在吴茱萸碱诱导a 375 -S2细胞死亡中的作用。
AIM: to compare the cytotoxic effect of evodiamine with chemotherapy drugs on A375-S2 cells, and to examine the relationship between the effects of PKC and ERK on evodiamine-induced cell death.
目的：对比吴茱萸碱与化疗药物对A375 - S2细胞的细胞毒活性，并且研究PKC及ERK激酶在吴茱萸碱诱导a 375 -S2细胞死亡中的作用。
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