Objective To utilize tail arterial and vein catheterization technique to perform hyperinsulinemic-euglycemic clamp in conscious rats and to evaluate this technique.
目的利用尾动静脉插管技术实施清醒状态下大鼠高胰岛素-正糖钳夹实验并对该技术进行评价。
Hyperinsulinemic-euglycemic clamp technique was considered to be gold standard for measurement of insulin sensitivity, and was applied further in the study of diabetes mellitus and drugs.
高胰岛素-正葡萄糖钳夹技术（简称正糖钳技术）已被公认为测定胰岛素敏感性的金标准，并在糖尿病及其治疗药物的研究中得到日益广泛且深入的应用。
Objective: Our aims were to establish the animal model of insulin resistance (IR) with high fatty diet and to evaluate it by using hyperinsulinemic euglycemic clamp technique.
目的：以钳夹技术评估高脂膳食建立胰岛素抵抗（IR）动物模型的可行性。
Objective: Our aims were to establish the animal model of insulin resistance (IR) with high fatty diet and to evaluate it by using hyperinsulinemic euglycemic clamp technique.
目的：以钳夹技术评估高脂膳食建立胰岛素抵抗（IR）动物模型的可行性。
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