ERK activity was measured by ERK1/2 immuno-precipitation kinase assay kit;
免疫沉淀法纯化蛋白并用ERK1/2试剂盒测定ERK活性；
Immunohistochemistry showed that ERK protein were mainly located in cytoplasm.
免疫组织化学显示ERK蛋白主要位于细胞浆内。
Conclusion: ERK negatively regulated the apoptosis induced by bufalin in K562 cells.
结论：ERK负向调节蟾蜍灵诱导的K562细胞凋亡过程。
Conclusion ERK expression was increased in the brain_heart syndrome caused by epilepsy.
结论erk在癫痫所引起的脑心综合征中有表达。
Because of the increased nitration the ERK pathway is impaired and the gastric mucosal healing is impaired.
由于ERK途径硝化增加受损，导致胃粘膜修复受损。
Objective: to study the mechanisms of oridonin-induced U937 cell apoptosis, and to examine the role of ERK MAPK.
目的：研究冬凌草甲素诱导人组织淋巴瘤u 937细胞凋亡的机制及ERK激酶在凋亡过程中的作用。
Disclosed are the ERK inhibitors of Formula (1.0) : and the pharmaceutically acceptable salts and solvates thereof.
所公开的是式(1.0)的ERK抑制剂；及其药学上可接受的盐和溶剂合物。
The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.
细胞外信号调节激酶是丝裂原激活蛋白激酶家族的重要成员。
Stimulation of this receptor in vitro results in up-regulation of activated extracellular signal–regulated kinase (ERK).
体外实验中对相应受体进行刺激后导致对细胞外信号调节酶（ERK）的激活有促进作用。
The morphological results showed that ERK signal transduction might be related to the differentiation of NSCs into neurons.
形态学初步证实ERK信号转导通路可能与神经干细胞向神经元分化有关。
To investigate the expression of extracellular signal-regulated kinase (ERK) and its significance in epithelial ovarian tumor.
探讨细胞外信号调节激酶(ERK)在卵巢上皮性肿瘤组织中的表达及其意义。
Objective Extracellular signal-regulated kinase (ERK) is closely related to cellular growth, differentiation and proliferation.
目的细胞外信号调节激酶(ERK)与细胞生长，分化，增殖等生理病理过程有密切关系。
It has been shown that its protective effect is related to protein kinase C (PKC) and extracellular signal-related kinase (ERK).
研究表明其保护效应与蛋白激酶C（PKC）和胞外信号调节激酶（ERK）有关。
Objective the aim was to observe the effect of lead on the activities of ERK in plasma of rat primary hippocampal neuron culture.
目的观察不同浓度和不同时间染铅对大鼠海马神经元培养细胞细胞质erk活性的影响。
Objective: To explore the effect of extracellular signal-regulated kinase(ERK) on the apoptosis induced by bufalin in K562 cells.
目的：探讨细胞外信号调解激酶（ERK）对蟾蜍灵诱导白血病细胞凋亡的影响。
Extracellular signal-regulated kinase (ERK) signaling pathway is a critical signaling pathway that transduce the intracellular signal.
细胞外信号调节激酶信号通道是一条重要的细胞内传导通道。
Conclusion GMCSF can up-regulate the expression of VEGF in human skin fibroblasts, and ERK pathway plays an important role in this process.
结论GMCSF可促进人皮肤成纤维细胞VEGF表达，ERK通路在此过程中发挥重要作用。
Methods The expression of ERK in spinal dorsal horn was detected by immunohistochemical method and was quantitated by western-blot analyses.
方法应用免疫组织化学方法检测erk在脊髓后角的定位表达，并用图像分析系统和免疫印迹法进行定量分析。
Conclusion: the level of ERK increased in hippocampus of rat model of AD, which showed changes of signal transduction route in the early phase.
结论：穹窿海马伞切断ad大鼠海马erk升高，说明erk信号转导途径在AD发病早期有改变。
Importantly, signaling studies revealed that the activation of ERK pathway was completely inhibited by Y356F and significantly reduced by Y327F.
更重要的是，信号通路研究显示erk的磷酸化可以被Y356F突变完全阻断或者被Y327F突变显著降低。
Objective: To investigate the expression of ERK signal transduction pathway and its significance in the cerebral cortex of rats after epileptic seizures.
目的：研究erk信号转导通路在癫痫发病机制中的作用。
Objective To decide whether the extracellular signal-regulated kinase (ERK) play a crucial role in PC12 differentiation induced by nerve-growth factor (NGF).
目的探讨细胞外信号调节激酶（ERK）在NGF诱导的PC12细胞分化中的作用机制。
Objective: to study the expressions of PTEN and extracellular signal-regulated kinase (ERK) and their clinical significance in tongue squamous cell carcinoma (TSCC).
目的：研究pten、细胞外信号调节激酶(ERK)表达及与舌鳞状细胞癌(TSCC)临床病理参数的关系。
OBJECTIVE To explore the effect of simvastatin on myocardial hypertrophy and the expression of extracellular signal-regulated kinases (ERK) in spontaneously hypertensive rat (SHR).
目的探讨辛伐他汀对自发性高血压大鼠（SHR）心肌肥厚及细胞外信号调节激酶（ERK）的影响。
Objective To investigate the correlation of ERK-1, ERK-2 and VEGF protein expression and the MVD counting and its clinicopathological role on the angiogenesis of colonic carcinoma.
目的分析erk - 1、ERK - 2与VEGF蛋白表达及结肠肿瘤微血管密度的关系，探讨ERK蛋白在结肠肿瘤血管形成中的临床意义。
Objective: To investigate the roles and relationships among ERK pathway, P53/P21 and CDK5/P35 during neuronal differentiation using a differentiative model of PC12 cells induced by NGF.
目的：利用NGF诱导的PC12细胞分化模型，探讨ERK通路、P53/P21蛋白和CDK5/P35蛋白在神经元分化过程中的可能作用及相互关系。
Objective: To investigate the expression of extracellular signal regulated protein kinase(ERK) signal transduction pathway and its significance in the rat brain after epileptic seizures.
目的：研究细胞外信号调节蛋白激酶（ERK）信号通路在癫痫大鼠脑内的表达规律及其意义。
Mitogen activated protein (MAP) kinase, also known as extracellular signal regulated kinase, or ERK, functions in neuronal signal transduction and participates in diverse development processes.
丝裂原激活的蛋白激酶又称细胞外信号调节激酶，具有神经元信号传导功能，参与多种发育过程。
AIM: to compare the cytotoxic effect of evodiamine with chemotherapy drugs on A375-S2 cells, and to examine the relationship between the effects of PKC and ERK on evodiamine-induced cell death.
目的：对比吴茱萸碱与化疗药物对A375 - S2细胞的细胞毒活性，并且研究PKC及ERK激酶在吴茱萸碱诱导a 375 -S2细胞死亡中的作用。
AIM: to compare the cytotoxic effect of evodiamine with chemotherapy drugs on A375-S2 cells, and to examine the relationship between the effects of PKC and ERK on evodiamine-induced cell death.
目的：对比吴茱萸碱与化疗药物对A375 - S2细胞的细胞毒活性，并且研究PKC及ERK激酶在吴茱萸碱诱导a 375 -S2细胞死亡中的作用。
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