This study was not only useful for the structure design of epothilone, but also provided a novel insight into the deeper mechanism of drug resistance.
本试验的研究成果为进一步改造埃博霉素和更加深入的研究抗耐药机制提供了理论指导和铺垫。
The invention also provides a fermentation method for producing the epothilone B by the fermentation culture of the sorangium cellulosum by using the sorangium cellulosum fermentation medium.
本发明还提供了使用本发明的纤维堆囊菌发酵培养基发酵培养纤维堆囊菌生产埃坡霉素B的发酵方法。
The invention also provides a fermentation method for producing the epothilone B by the fermentation culture of the sorangium cellulosum by using the sorangium cellulosum fermentation medium.
本发明还提供了使用本发明的纤维堆囊菌发酵培养基发酵培养纤维堆囊菌生产埃坡霉素B的发酵方法。
应用推荐