After studying 500 patients with rashes, researchers found high levels of elafin only in those with rashes from GVHD.
通过研究500位发生皮疹的患者，研究者发现只有那些由于GVHD引发的皮疹会导致升高的弹力素。
Elafin is produced in the surface layer of skin cells in response to specific inflammatory proteins involved in GVHD.
弹力素是由GVHD引发特异性炎症的皮肤表层皮肤细胞分泌。
After 12 months, three times as many patients in the high-elafin group had died from GVHD and its complications than in the low-elafin group.
12个月之后，第一组移植物抗宿主病死亡率和并发症发病率是第二组的三倍。
"In the future, we hope a clinician might be able to test the elafin levels of a transplant patient. To decide with a rash whether to initiate treatment," says Ferrara.
费拉拉说：“今后，我们有希望使临床医生能够通过对骨髓病人抑弹性酶蛋白含量的检测，确定对出现皮疹的病人要不要采取治疗措施。”
They compared levels of elafin — an anti-inflammatory protein produced by the body in response to skin GVHD — in 10 patients who had developed the disease and 20 patients who had not.
他们选取了10个患有皮肤GVHD的病人和20个没有得这种病的病人，对比了两类病人血样中的弹力素水平。弹力素是由于身体对皮肤GVHD作出反应而产生的一种抗炎蛋白。
Scientists used mass spectrometry to screen a large number of proteins in the blood and skin of bone marrow transplant recipients searching for biomarkers, and elafin appeared to be significant.
科学家们应用质谱分析法筛查了骨髓移植受者外周血和皮肤中大量蛋白质以寻找合适的生物标记，弹力素被发现显著改变。
Scientists used mass spectrometry to screen a large number of proteins in the blood and skin of bone marrow transplant recipients searching for biomarkers, and elafin appeared to be significant.
科学家们应用质谱分析法筛查了骨髓移植受者外周血和皮肤中大量蛋白质以寻找合适的生物标记，弹力素被发现显著改变。
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