Objective: To induce the EAE model on Guinea pig wi th Myelin Basic Protein (MBP).
目的:用髓鞘碱性蛋白(MBP)诱导实验性变态反应性脑脊髓炎(eae)豚鼠模型。
Method: Establishing the EAE model and detecting the expression and distribution of MMP-2 and -9 in different type EAE with the method of IHC.
方法:建立多病程大鼠eae模型,以免疫组化的方法检测MMP - 2、MMP -9在不同类型EAE中的表达及分布。
Methods Guineapigs were induced to establish EAE model by injecting guineapig with spinal cord homogenate (GPSCH) in complete Freund's adjuvant (CFA) bordetella pertussis vaccine (BPV).
方法采用注射完全福(氏)佐剂-豚鼠全脊髓匀浆(CFA-GPSCH) ,并辅以注射百日咳疫苗( BPV) ,诱导豚鼠EAE模型。
The model of experimental allergic encephalomyelitis (EAE) was successfully established in guinea pigs by using the complete Fruend s adjuvant and myelin basic protein.
采用完全弗氏佐剂和碱性髓鞘蛋白成功地诱发了实验性过敏性脊髓炎(EAE)豚鼠模型。
Objective:To establish the experimental autoimmune encephalomyelitis(EAE) model on Guinea Pig with pan-spinal cord homogenate(coarse myelin basic protein, cMBP).
目的:用全脊髓匀浆(粗制髓鞘碱性蛋白)建立豚鼠实验性自身免疫性脑脊髓炎(EAE)模型。
"This puts an emphasis on the fact that blood brain permeability changes are an important aspect of the development of a CNS inflammatory disease like EAE, an animal model of MS," he says.
同时他还说:“这个研究结果强调了这样一个事实——血脑屏障的通透性改变是发生象实验性变应性脑脊髓炎(一种多发性硬化病的动物模型)这类中枢神经系统感染性疾病的重要因素。”
Objective To construct animal model for further elucidating the pathogenesis of experimental allergic encephalomyelitis (EAE).
目的建立实验性变应性脑脊髓炎(eae)动物模型,为进一步研究其发病机制提供依据。
Objective to establish the animal model of EAE (experimental autoimmune encephalomyelitis) to study the inducible suppression of EAE by i. p. administration of soluble MBP (myelin basic protein).
目的建立实验性自身免疫性脑脊髓炎(eae)动物模型,研究腹腔内注射可溶性髓鞘碱性蛋白(MBP)诱导免疫耐受的作用机制。
Objective to establish the animal model of EAE (experimental autoimmune encephalomyelitis) to study the inducible suppression of EAE by i. p. administration of soluble MBP (myelin basic protein).
目的建立实验性自身免疫性脑脊髓炎(eae)动物模型,研究腹腔内注射可溶性髓鞘碱性蛋白(MBP)诱导免疫耐受的作用机制。
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