• One telltale sign is that the strain does not contain the eae gene, which codes for a protein called intimin, an adhesion protein that allows the bacteria to attach to cells in the gut.

    一个危险信号是EHEC并不携带eae基因,这种基因编码一种叫做intimin的黏附蛋白。

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  • Objective:To study the curative effect of EAE with DT390-IL2 recombinant plasmid.

    目的:研究DT390-IL2重组质粒对实验性变态反应性脑脊髓炎(EAE)的治疗效果。

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  • Methods The female guinea pigs were divided randomly into control group, EAE group and i. p. MBP group.

    方法将雌性豚鼠随机分为对照组、EAE组和腹腔注射MBP组。

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  • Magnetic transfer imaging, together with USPIO enhancement scan, was helpful to determine the features of the EAE lesions.

    与uspio增强扫描相结合,磁化传递成像能够提示EAE病变的性质。

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  • Objective To construct animal model for further elucidating the pathogenesis of experimental allergic encephalomyelitis (EAE).

    目的建立实验性变应性脑脊髓炎(eae)动物模型,为进一步研究其发病机制提供依据。

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  • Conclusions Blood brain barrier damage during the earlier period of EAE might play an important role in the pathogenesis of EAE.

    结论血-脑脊液屏障的早期损害在EAE发病过程中具关键作用。

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  • Objective: to investigate the apoptotic cell in the peripheral lymphoid organs in experimental autoimmune encephalomyelitis (EAE) rats.

    前言:目的:研究实验性变态反应性脑脊髓炎(eae)大鼠外周免疫器官中细胞凋亡的情况。

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  • The results of HPLC analysis showed that the main components of EAE and BE were flavonoids, including naringin, rhoifolin and quercitin.

    HPLC分析结果显示乙酸乙酯合并正丁醇部位主要成分为柚皮苷、野漆树苷和槲皮素等黄酮类化合物。

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  • Oral tolerance by feeding autoantigens is an effective method to prevent EAE and to treat MS, which mechanism has not been made very clear.

    小剂量口服自身抗原诱导免疫耐受可有效地抑制EAE和MS,这已被诸多研究所证实,但其机制尚不清楚。

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  • Objective to explore the surface molecule changes of the experimental autoimmune encephalomyelitis (EAE) rat brain vascular endothelial cells.

    目的探讨实验性自身免疫性脑脊髓炎(eae)大鼠脑血管内皮细胞表面分子的改变。

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  • Method: Establishing the EAE model and detecting the expression and distribution of MMP-2 and -9 in different type EAE with the method of IHC.

    方法:建立多病程大鼠eae模型,以免疫组化的方法检测MMP - 2、MMP -9在不同类型EAE中的表达及分布。

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  • The MTR value of USPIO enhancement area for the first time was significantly different from MTR of the same area of the last scan in EAE rats(P<0.05).

    EAE组大鼠USPIO异常强化区的MTR值与出现强化前同一区域的MTR值相比差异具有显著性(P<0.05)。

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  • Experimental allergic encephalomyelitis (EAE) is an immune disease, whose character is the damage of white matter of nervous system mediated by immunocyte.

    实验性自身免疫性脑脊髓炎(eae)是一种免疫细胞介导的以中枢神经系统白质损坏为特征的自身免疫性疾病。

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  • Objective:To establish the experimental autoimmune encephalomyelitis(EAE) model on Guinea Pig with pan-spinal cord homogenate(coarse myelin basic protein, cMBP).

    目的:用全脊髓匀浆(粗制髓鞘碱性蛋白)建立豚鼠实验性自身免疫性脑脊髓炎(EAE)模型。

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  • The model of experimental allergic encephalomyelitis (EAE) was successfully established in guinea pigs by using the complete Fruend s adjuvant and myelin basic protein.

    采用完全弗氏佐剂和碱性髓鞘蛋白成功地诱发了实验性过敏性脊髓炎(EAE)豚鼠模型。

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  • Conclusion: GBE can delay demyelination process in EAE mice by inhibiting microglial activation, suggesting that GBE has potential to treat multiple sclerosis in future.

    结论:GBE可能通过抑制小胶质细胞激活从而延缓EAE小鼠脱髓鞘进程,提示GBE对多发性硬化具有一定的治疗作用。

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  • Conclusion High atorvastatin plays a protective role in rats with EAE and its mechanism may be involved in some impact on the immunological mechanism of the central nerve system.

    结论高剂量阿托伐他汀对EAE大鼠有保护作用,可能与其对中枢神经系统的免疫机制有一定影响有关。

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  • Methods Guineapigs were induced to establish EAE model by injecting guineapig with spinal cord homogenate (GPSCH) in complete Freund's adjuvant (CFA) bordetella pertussis vaccine (BPV).

    方法采用注射完全福(氏)佐剂-豚鼠全脊髓匀浆(CFA-GPSCH) ,并辅以注射百日咳疫苗( BPV) ,诱导豚鼠EAE模型。

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  • Objective to establish the animal model of EAE (experimental autoimmune encephalomyelitis) to study the inducible suppression of EAE by i. p. administration of soluble MBP (myelin basic protein).

    目的建立实验性自身免疫性脑脊髓炎(eae)动物模型,研究腹腔内注射可溶性髓鞘碱性蛋白(MBP)诱导免疫耐受的作用机制。

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  • Objective to establish the animal model of EAE (experimental autoimmune encephalomyelitis) to study the inducible suppression of EAE by i. p. administration of soluble MBP (myelin basic protein).

    目的建立实验性自身免疫性脑脊髓炎(eae)动物模型,研究腹腔内注射可溶性髓鞘碱性蛋白(MBP)诱导免疫耐受的作用机制。

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