In addition to the familiar duplex DNA, certain G-rich DNA sequences can fold into a variety of four-stranded structures, which are called G-quadruplexes.
富含鸟嘌呤碱基的DNA序列能够通过鸟嘌呤环的互联作用形成四链螺旋结构，这种结构被称为G-四链体。
It revealed that imide derivative 4, a potent binder of HIV-1 DNA, had the higher binding affinity with the duplex DNA among six DNA-recognizing mole-cules.
在研究中比较了不同识别分子与靶序列DNA结合的强弱，发现双萘酰亚胺衍生物4对此序列DNA具有高亲合性的结合，并分析了识别分子与DNA复合物的碎裂机理以及结合模式。
The stability of these triple helixes is so high that homopyrimidine PNA targeted to purine tracts of dsDNA invades the duplex by displacing one of the DNA strands.
这种三螺旋体的稳定性极高，以至于在同型嘧啶PNA靶向双链DNA嘌呤道时，能取代其中一条DNA链侵入双螺旋。
Objective To investigate the value of duplex polymerase chain reaction (DPCR) in early diagnosis of Legionella pneumonia by detecting Legionella DNA in sputum and bronchoalvelar lavage fluid(BALF).
目的探讨双重聚合酶链反应（DPCR）法检测痰及支气管肺泡灌洗液（BALF）中军团菌DNA在早期诊断军团菌肺炎的意义。
Thus, the Tm of PNA–DNA duplex is barely affected by low ionic strength. This significantly facilitates the hybridization with the PNAs.
因此，PNA-DNA的热熔温度几乎不受弱离子强度的影响，十分有利于PNA的杂交。
Thus, the Tm of PNA–DNA duplex is barely affected by low ionic strength. This significantly facilitates the hybridization with the PNAs.
因此，PNA-DNA的热熔温度几乎不受弱离子强度的影响，十分有利于PNA的杂交。
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