Objective to evaluate the effect of delayed type hypersensitivity (DTH) and CD8 t lymphocyte cytotoxicity intervention on the development of chronic rejection in mouse cardiac allografts.
目的探讨干预慢性迟发性超敏反应(DTH)与CD 8 +T淋巴细胞的细胞毒等效应机制对同种小鼠心脏移植后慢性排斥反应的影响。
RESULTS: In comparison with control group, the DTH and antigen specific lymphocyte proliferation reaction in oral tolerance group were suppressed significantly;
结果：与对照组相比较，口服耐受组大鼠DTH和抗原特异性淋巴细胞增殖反应明显受抑制；
In the DTH model, UANa enhanced the degree of allergen-induced ear swelling and promoted the ability of lymphocyte proliferation in vitro.
DTH模型中，尿酸钠增强致敏原引发的耳廓肿胀程度，并促进DTH小鼠淋巴细胞的体外增殖能力。
Recipient B6 mice were characterized for the tolerance status with donor Lewis rat skin graft, mixed lymphocyte reaction (MLR), and delayed - type hypersensitivity (DTH) assays after 30 days.
于耐受诱导后30 d对受体小鼠作耐受状态的检查，包括供体特异性皮肤移植、混合淋巴细胞反应(MLR)及迟发型超敏反应(DTH)。
Recipient B6 mice were characterized for the tolerance status with donor Lewis rat skin graft, mixed lymphocyte reaction (MLR), and delayed - type hypersensitivity (DTH) assays after 30 days.
于耐受诱导后30 d对受体小鼠作耐受状态的检查，包括供体特异性皮肤移植、混合淋巴细胞反应(MLR)及迟发型超敏反应(DTH)。
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