• The higher drug loading, the faster drug release.

    植入剂中药物含量越大、释放越快;

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  • The drug loading of the Hep-CPT conjugate was 7.2%.

    高效液相色谱法测得它的载药量为7.2%。

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  • Comparing to CSO-SA micelles, DOX-CSO-SA micelles showed better ability of drug loading capacity.

    研究结果显示,DOX - CSO - SA聚合物胶团的载药能力较CSO - SA聚合物胶团强。

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  • Adriamycin HCl (ADM) was used as a model drug to study the drug loading property of the microcapsule.

    以阿霉素为模型药初步研究其载药性能。

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  • RESULTS Amphiphilic chitosan derivation may form drug loading micelle in the water, which has good drug loading capability.

    结论两亲性壳聚糖衍生物可能具有良好的载药性,是一种良好的药用辅料。

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  • Considered the application in nanomedicine, the effect of the diverse morphologies on drug loading efficiency was also investigated.

    同时,不同形貌的聚醚-聚酸酐三元共聚物胶束在载药效率和载药量上有明显差别。

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  • Factors influencing the drug release rate, including drug loading, species and amount of additives, hardness, particle size were studied.

    考察载药量、填充剂种类和用量、硬度、辅料粒径等因素对药物释放的影响。

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  • Abstract: Response surface methodology was applied to optimize the drug loading rate of persimmon leaf total flavonoids sustained release pellets.

    摘要:本文研究了响应面法优化柿叶总黄酮缓释微丸的载药量。

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  • Liposomes are promising drug targeting and controlled release systems, because of their good safety, biocompatibility and drug loading capability.

    脂质体由于具有高度安全性、生物相容性、广泛的载药性等特点,是极具研发前景的靶向、缓释药物载体。

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  • The results indicated that the microspheres had poor drug loading and entrapment efficiency abilities due to residual impurities contained in polymer.

    初步分析表明,因聚合物中残留的微小杂质的影响,造成了所制备的载药微球过低的载药量及包封率。

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  • The drug loading rate, encapsulation efficiency, particle distribution and in vitro release of Lac-NCTD from liposomes were investigated, respectively.

    考察了药物与磷脂的复合率,磷脂复合物脂质体的包封率,粒径大小和分布,以及体外释药特性。

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  • OBJECTIVE To study the preparation of aciclovir loaded albumin microspheres (ACV BSA MS) and evaluate its morphology, drug loading and release in vitro.

    目的优化阿昔洛韦白蛋白微球的制备工艺,并对其形态学性质、载药量、体外释药进行考察。

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  • Besides, from the view of the efficiency of drug release, the higher content of the drug loading, the more the drug residues in the nano-tubes relatively.

    同时,从药物最终的释放效率来看,载药量越高,纳米管中的药物残留也相对越多。

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  • The preparation method has the advantages of simplicity, easy operation, high ratio of drug loading and low cost, and can realize automated and large-scale production.

    该制备方法简单易行,载药率高,成本低,可实现自动化和规模化生产。

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  • The drug loading, entrapment efficiency, diameter of nanoparticles and particle diameter distribution, shape and release curve of nanoparticles were investigated in vitro.

    对纳米粒的载药量、大小及分布、形态及体外释放等进行了研究。

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  • The encapsulation efficiency and drug loading of triptolide-loaded poly (d, L-lactic acid) nanoparticles were analyzed by RP-HPLC and ultracentrifuge method in this study.

    本文研究了反相高效液相色谱和超速冷冻离心测定雷公藤甲素聚乳酸纳米粒包封率和载药量的方法。

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  • “People had done all kinds of fancy things, but the problem with a lot of the methods was that the actual drug loading was very low, ” Kohane said. “It’s not clear why no one did this before.

    “人们做过很多奇特的设计,但很多方法存在的问题是实际载药量太低,”科汉说,“不明白以前为什么没有人这么做,好像我们发明了三明治”

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  • Conclusion: The HCPT-SSLN has high entrapment efficiency and drug loading, uniform particle size, good stability, which initially indicates that HCPT is fit for being incorporated into SSLN.

    结论:本实验制备的HCPT - SSLN包封率和载药量较高,粒径分布均匀,稳定性良好。初步表明HCPT适合进行SSLN包裹。

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  • Results showed that only when the CH331 particles were pretreated with a suitable amount of ethanol could lead to more uniform sizes, better appearance and higher drug loading for the microspheres.

    研究发现,只有加入适量乙醇作为药物颗粒预处理剂才能制得形态圆整、粒径均一且具有较高载药量的微球。

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  • The drug releasing curve of the multilayer film loading drug indicates that the drug releasing mode is diffusion and releasing period is about 45 days.

    该载药生物活性多层膜的药物释放曲线表明,该含药多层膜系统的药物释放方式为扩散方式,释放周期是45天左右。

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  • The drug-loading rate of this chitosan-levofloxacin sustained-release microsphere is 43.88%. Its in vitro dissolubility is good.

    该方法制备的左氧氟沙星-壳聚糖缓释微球载药量为43.88%,体外累积释放度的线形关系良好。

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  • The in vitro test of IBU loading and release illustrated the system had a great potential use for thermo-responsive controlled drug-release.

    对最终体系进行的体外药物布洛芬(IBU)的装载和释放测试表明,该体系在温度响应控制药物释放方面有着较大的潜在应用前景。

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  • Compared to microspheres with low water absorbing rate, the high batches had higher drug-loading rate and entrapment rate.

    吸水度高的微球载药量和包封率较吸水度低的微球高。

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  • The invention relates to a poly-lactic acid fiber loading a powder drug and a preparation method thereof.

    本发明涉及一种装载粉末型药物的聚乳酸纤维及其制备方法。

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  • Optimization of preparation and formulation was accomplished by evaluating the drug-loading amounts and the entrapment efficiency of luteolin liposomes.

    方法采用薄膜分散法和冻干工艺进行木犀草素脂质体制备,并以载药量、包封率为评价指标,优化制备处方和工艺。

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  • The preparations of drug-loading particles and excipients particles and selection of excipients are reviewed.

    综述了其中载药微粒和辅料颗粒的制备方法、辅料的选择等研究概况。

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  • The technology of orally disintegrating tablets prepared with drug-loading enteric coated particles or sustained-release particles and appropriate excipients is introduced.

    介绍了将药物制成肠溶或缓释的微粒后再与适宜的辅料压制得到微粒型口腔崩解片的技术。

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  • Samples of different processing on drug-loading rate has a certain influence.

    不同的处理过程对样品的载药率也有一定的影响。

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  • In NLC drug delivery systems, the compatibility of drug and lipid carriers is the key element to determine the structure of microscopic and mesoscopic, drug-loading capacity and stability.

    在NLC给药系统中,药物与载体以及脂质载体之间的相容性是决定NLC的微观和介观结构,载药能力,稳定性等药剂学性质的关键因素。

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  • In NLC drug delivery systems, the compatibility of drug and lipid carriers is the key element to determine the structure of microscopic and mesoscopic, drug-loading capacity and stability.

    在NLC给药系统中,药物与载体以及脂质载体之间的相容性是决定NLC的微观和介观结构,载药能力,稳定性等药剂学性质的关键因素。

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