Objective To evaluate the effect of craniotomy on the CSF drug concentration by measuring drug concentration in blood, in subcutaneous transudation and in CSF.
目的通过测定开颅术后周围静脉血、皮下引流液及脑脊液中药物浓度，来评价开颅手术对脑脊液药物浓度的影响。
Conclusions there is a significant individual variation in the pharmacokinetic parameters, therefore, the dose should be individualized on the basis of blood drug concentration monitoring.
结论老年心衰病人的个体药代动力学参数波动范围大，个体差异更为突出，临床应在血药浓度监测的基础上实行最佳个体化给药。
RESULTS:71.7% of the results of blood drug concentration were in the reference range.
结果：71.7%患者的血药浓度结果在参考范围内；
So clinically, to monitor the blood concentration plays a very important part in implementing individualized and rationalized medication, as well as in reduction of drug poisoning when using digoxin.
所以临床在用药过程中，药物浓度的监测对实施个体化、合理化用药，减少药物中毒的发生起着重要作用。
PAE suggest that the sum of drug effective time is a combination of PAE and the time that anti-microbial concentration above the MIC in blood.
抗菌后效应的存在提示药物对细菌作用的时间应为血药浓度高于MIC的时间与PAE时间之和。
Method: Drug concentration of TFH and TFH-SLN in blood, heart, liver, spleen and kidney of mice after oral administration was determined by HPLC.
方法：采用HPLC法测定小鼠口服醋柳黄酮（TFH）和TFH-SLN后血液、心、肝、脾、肾的药物浓度。
Objective To investigate the most appropriate drug concentration in making animal model of blood-stasis with adrenalin.
目的探讨用肾上腺素法进行血瘀证动物模型造模时的最适浓度。
In patients with hypertension, the plasma drug concentration and blood pressure versus time curves mirrored each other, indicating a close relationship between concentration and effect.
在高血压患者中，药物血浆浓度与血压-时间曲线相互对应，这表明药物浓度与降压疗效之间密切相关。
Radiation therapy for tumors is that radioactive substances is directly placed in the tumor residual cavity, to avoid the blood-brain barrier and improve local drug concentration.
瘤内放射治疗是将放射性药物直接置于肿瘤残腔内，直接作用于胶质瘤细胞，此法能避开血脑屏障同时也能提高局部药物浓度。
Radiation therapy for tumors is that radioactive substances is directly placed in the tumor residual cavity, to avoid the blood-brain barrier and improve local drug concentration.
瘤内放射治疗是将放射性药物直接置于肿瘤残腔内，直接作用于胶质瘤细胞，此法能避开血脑屏障同时也能提高局部药物浓度。
应用推荐