OBJECTIVE To investigate the effect of drug concentration, drug structure of fluoroquinolones on the resistant gene of Escherichia coli mutants selected in the mutant selection window (MSW).
目的：研究不同药物浓度、不同化学结构的氟喹诺酮类药物对突变选择窗(MSW)内筛选的大肠埃希菌耐药突变体的靶位耐药基因的影响。
Objective To evaluate the effect of craniotomy on the CSF drug concentration by measuring drug concentration in blood, in subcutaneous transudation and in CSF.
目的通过测定开颅术后周围静脉血、皮下引流液及脑脊液中药物浓度，来评价开颅手术对脑脊液药物浓度的影响。
Conclusion Tumor metastasis status of rectal cancer lymph nodes exerts insignificant effect on drug concentration for LC and RERC.
结论直肠癌淋巴结转移状态对RERC和LC淋巴结内药物浓度聚集无明显影响。
Objective: to examine modulating effect of Sandostatin to lymph drug concentration following intraperitoneal chemotherapy.
目的：探讨善得定对腹腔化疗时淋巴药物浓度的调节作用。
Objective To explore the effect of clonazepam (CZP) on background EEG activities and epileptiform discharges, and the relationship between the effects and the serum drug concentration.
目的了解氯硝西潘对脑电背景活动、样放电的影响，及其与氯硝西潘血清浓度的关系。
CONCLUSION: GLM could enhance the cytotoxic effect of ADM on drug resistant cell and increase intracellular drug concentration in a concentration dependent fashion.
结论：GLM提取物可提高了ADM对耐药细胞的细胞毒作用，增加了耐药细胞内药物浓度，且呈剂量依赖性。
The results of HPLC showed that pharmacological effect of prodigiosin dependent on drug concentration in cells.
HPLC结果显示，灵菌红素的药理学作用与细胞内药物浓度相关。
In patients with hypertension, the plasma drug concentration and blood pressure versus time curves mirrored each other, indicating a close relationship between concentration and effect.
在高血压患者中，药物血浆浓度与血压-时间曲线相互对应，这表明药物浓度与降压疗效之间密切相关。
RESULTS The drug effect of the compound injection was better than that of procaine or lidocaine hydrochloride injection in same concentration.
结果：复方盐酸普鲁卡因注射液药效均强于相同浓度的盐酸普鲁卡因与盐酸利多卡因。
AIM: To investigate the effect of Xiaoyaosan drug-containing serum on proliferation and differentiation of hippocampus nerve precursor cells under high corticosterone concentration condition.
目的：观察中药复方逍遥散含药血清对高浓度皮质酮环境下海马神经前体细胞增殖和分化的影响。
METHODS The effect of cholesterol content, lipid-drug ratio, incubation time and temperature, and calcium acetate concentration on entrapment efficiency was studied.
方法以包封率为指标，考察阿魏酸脂质体胆固醇含量、脂药比、孵育时间、孵育温度、钙离子浓度等因素对包封率的影响。
Results The inhibitory effect of kaemperol on H446 cells were significantly increased with the drug concentrations(P<0.01), and the effect was in a concentration-dependent manner in vitro.
结果不同浓度的山奈酚能抑制人小细胞肺癌H446细胞生长，且随浓度增加抑制作用增强（P<0.01）。
Fluorouracil for implantation can elevate the local drug concentration, extend the time of effective drug concentration, reduce the general toxic and side-effect.
氟尿嘧啶植入剂可提高局部药物浓度，延长有效药物浓度时间，降低全身毒副反用。
Many researches indicated that there is correlation between antifungal drug blood concentration and therapeutic effect.
另有研究也证实抗真菌药的血药浓度与其毒副作用具有相关性。
Meropenem did not have complete bactericidal effect and more bacterial endotoxin could be released at lower drug concentration.
美洛培南杀菌作用不完全且诱导细菌呈纺垂体样改变，可能导致内毒素释放增加，影响临床严重感染的预后。
Meropenem did not have complete bactericidal effect and more bacterial endotoxin could be released at lower drug concentration.
美洛培南杀菌作用不完全且诱导细菌呈纺垂体样改变，可能导致内毒素释放增加，影响临床严重感染的预后。
应用推荐