DR5 may play an important role in TRAIL-inducing apoptosis of AML cells.
DR5在TRAIL介导的急性髓系白血病细胞凋亡中起重要的作用。
Objective: to study the role of DR5 in TRAIL apoptotic signal transduction.
目的:研究DR5在介导TRAIL凋亡信号中的作用。
METHODS: DR5 expression on HL7702 cell surface was determined by flow cytometry (FCM).
方法:流式细胞术检测HL 7702细胞表面dr5的表达。
Objective to investigate the influence of death receptor 5 (DR5) in the proliferation of nerve cells.
目的探讨死亡受体5 (DR5)对神经细胞增殖的影响。
Immunohistochemistry and FCM were used to detect the expression of TRAIL and its death receptors (DR4 and DR5).
免疫组化和流式细胞术检测肾脏TRAIL基因及其死亡受体DR 4、DR5的蛋白表达。
The expression of cell surface-bound DR4 and DR5 were determined by indirect fluorescence staining and flow cytometry analysis.
用间接免疫荧光染色结合流式细胞技术检测细胞表面DR4和DR5分子表达;
Results: DR5 primarily was located in the cytoplasm and on the surfaces of EC9706 cells, mainly in the cytoplasm but not in the nuclei.
结果:DR 5分布在食管癌ec9706细胞的细胞质和细胞膜表面,主要在细胞质,但在细胞核没有DR 5分布,而且在悬浮的食管癌细胞表面dr5表达高于铺展者。
AIM to reveal the expression of death receptor 5 (DR5) in the cells of acute non lymphocyte leukemia (ANLL) and its clinical significance.
目的探讨死亡受体dr5在急性非淋巴细胞白血病(ANL L)细胞中的表达及其临床意义。
Objective: to construct eukaryotic expression vector of human death receptor (DR5) and transfect NS-1 cells to establish stable NS-1 cell line.
目的:构建人死亡受体5 (DR5)真核表达载体,转染NS - 1细胞,建立稳定转染的NS - 1细胞系。
Results: The expression of death receptor 5 (DR5) was certificated in U343, DR5 appeared to be located in intracellular perinuclear compartment.
结果:神经胶质瘤细胞株u343表达死亡受体DR5, DR 5分布于细胞内细胞核的周围。
The binding ability of these deletant proteins to AD5-10, a mouse anti-human DR5 monoclonal antibody, was evaluated by immunoblotting and ELISA.
利用蛋白免疫印迹及ELISA技术研究重组蛋白与小鼠抗人DR5单克隆抗体AD5-10的结合情况。
Objective:To reveal the relationship between cell spreading and DR5 distribution on the cell surfaces of human esophageal carcinoma EC9706 cell line.
目的:探讨食管癌鳞癌EC9706细胞系细胞表面DR5的表达分布与细胞铺展状态的关系。
Methods Immunohistochemistry and in situ quantification methods were used to observe the expression and the variation of TRAIL and its receptors DR4 and DR5 in human placenta during pregnancy.
方法免疫组织化学结合图像分析定量方法观察TRAIL及其DR4、DR5受体在人胎盘组织的表达及其含量的周龄变化。
Objective to investigate the correlation between sensitivity to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and expression level of death receptor 5 (DR5) on tumor cell surface.
目的探讨肿瘤细胞表面dr5表达水平与其对肿瘤坏死因子相关的凋亡诱导配体(TRAIL)敏感性之间的关系。
Objective to investigate the correlation between sensitivity to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and expression level of death receptor 5 (DR5) on tumor cell surface.
目的探讨肿瘤细胞表面dr5表达水平与其对肿瘤坏死因子相关的凋亡诱导配体(TRAIL)敏感性之间的关系。
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