All the effects were in a time and dose dependent manner.
上述作用均呈时间和剂量依赖性。
The toxic effects were reversible and were dose dependent.
中毒反应是可恢复的，反应程度与用药剂量有关。
Results: (1) There was dose dependent effect of zinc on the neuron survival.
结果(1)锌促进神经细胞的存活作用具有剂量效应关系。
The fracture risk is dose dependent and occurs rapidly after the start of treatment.
这种骨折是剂量依赖性的，并且在治疗开始后很快发生。
RESULTS: AMHCA was able to induce cardiomyocyte apoptosis in a dose dependent manner.
结果：AMHCA诱导的心肌细胞凋亡具有剂量依赖性。
Aspirin could rescue Y79 cells from hyperthermia induced apoptosis in a dose dependent manner.
阿斯匹林可抑制热诱导的Y79细胞的凋亡，也呈剂量依赖性。
Pharmacodynamic assay has shown that inhibition of proteasome is dose dependent and reversible.
药效学分析表明蛋白酶体抑制药的抑制作用有剂量依赖性和可逆性。
The inhibition of JSL to the amplitude and frequency of gastric myoelectric activity was dose dependent.
静松灵对犬胃肌电频率和振幅的影响有剂量相关性；
ATRA could induce morphological differentiation and inhibit growth of SY5Y cells and showed time and dose dependent manner.
ATRA对SY5Y细胞有抗增殖作用和诱导细胞分化作用，并呈一定时间和剂量依赖关系。
Results Venenum Bufonis had growth inhibitory and apoptosis-inducing effects on U2OS cell with a time and dose dependent relation.
结果蟾酥水提取物对U2 OS细胞具有生长抑制及诱导凋亡作用，且呈时间依赖和剂量依赖。
Inflammatory changes including neutrophil and monocyte, lymphocyte hyperplasia were observed on pulmonary pathological slide in a dose dependent.
肺组织病理切片有炎性改变，单核细胞和中性粒细胞浸润和淋巴细胞增生，有剂量效应关系。
Results IL 6 up regulated the expression of CD14 and down regulated the expression of SR in a time and dose dependent fashion at the level of mRNA.
结果在基因转录水平，IL6对CD14表达呈时间剂量依赖性上调，对SR的表达呈进行性下调；
Results:Compared with control group, quercetin or tanshione treatment resulted in a dose dependent decrease of hemolytic degree and MDA content of RBC( P< 0.01).
结果：槲皮素组和丹参组的溶血度及MDA的含量均低于损伤组（P <0 .0 1） ，且与药物浓度有一定的量效关系。
Conclusion progesterone was involved directly in osteocalcin production by regulating gene expression and this effect of progesterone was time and dose dependent.
结论孕酮从基因水平调节离体胎鼠成骨细胞骨钙素的生成，这种调节呈现时间及剂量依赖。
CONCLUSION Acetazolamide decreased the osmotic water permeability induced by AQP1 and inhibited the water transporting function of AQP1 in a dose dependent manner.
结论乙酰唑胺剂量依赖性地降低AQP1介导的渗透水通透性，抑制AQP1转运水的功能。
Results The result of LDH leakage showed that indomethacin could induce the injury of RGM-1 in a dose dependent manner and LPS could lessen it significantly (P<0.05).
结果低浓度的吲哚美辛即可引起RGM-1细胞受损并且呈量效关系，LPS可以明显减轻这一作用（P<0.05）；
Method: the whole cell patch clamp recording technique was used in this study. Results: blood resin suppressed amplitude of the sodium channel currents in a dose dependent way.
方法：采用全细胞膜片钳记录法，在新鲜分离的大鼠背根神经节细胞上观察血竭对钠通道电流幅值的影响。
In addition, the withdrawal symptoms precipitated by naloxone in morphine dependent rats were blocked by methoctramine(ip) or pirenzepine (it) at single dose injection in a dose dependent manner.
美索四氨或哌拉唑嗪以剂量依赖方式抑制吗啡依赖大鼠纳洛酮激发的戒断症状。
Results: Hydrosalpinx fluid significantly decreased the hatching rate of blastocysts and the concentrations of MMP-9 and TIMP-1 both in blastocysts and culture medium, in a dose dependent manner.
结果输卵管积液组的囊胚孵出率低于无积液组，囊胚及培养液中的MMP-9和TIMP-1低于无积液组，并呈剂量依赖性，MMP-9/TIMP-1随积液浓度增加而降低。
The effect of the hormone was time and dose-dependent.
激素的作用呈时间及剂量依赖性。
Conclusion The erythropoiesis inhibitors might exist in uremia sera which had a dose-dependent inhibitory effects on CFU-E and BFU-E proliferations.
结论尿毒症患者血清中存在红细胞生成抑制因子，其对红系造血祖细胞的抑制作用具有剂量依赖性。
Bleomyin, an anti - neoplastic agent, is well known to induce- dose - dependent lung injury and pulmonary fibrosis in both humans and animals.
博莱霉素是一种抗肿瘤药物，普遍认为在人体和动物模型内均可产生剂量依赖型的肺损伤和肺纤维化。
Leptin administration led to increased proliferation of rat NP cells in a dose-dependent manner, as shown by MTT assay and by counting the percentage of PCNA-positive cells.
正如MTT法和计数pcna阳性细胞比例所显示：瘦素的给予与鼠np细胞的增殖成剂量依赖性关系。
Results HDI could inhibit the proliferation of SPC-A-1 cells and inhibitory effect was dose-dependent.
结果白花蛇舌草注射液能抑制SPC-A-1细胞增殖，且呈剂量依赖性；
Results: Paclitaxel inhibited the growth of A375 cells by inducing apoptosis in a both time-dependent and dose-dependent manner(P<0.01).
结果：紫杉醇通过诱导细胞凋亡抑制A375细胞生长，并呈时间和剂量依赖性（P<0.01）；
The results showed that SM increased the blood flow of brain and cerebral cortex in a dose-dependent manner and had no effect on the blood flow of femoral arteries.
结果表明，桑葛合剂可以明显增加兔脑及大脑皮层的血流量，且呈剂量依赖性，但对股动脉血流量则无明显影响；
Conclusion CTX SO3 could inhibit the CNS of mice and cause a dose-dependent tremor, which may be related to the central 5-ht system.
结论芋螺毒素so3对小鼠神经系统有一定抑制作用，同时伴有剂量依赖性震颤，其机制可能与中枢5 -羟色胺系统有关。
Results: APN could inhibit the ADP-induced platelet aggregation in vitro in a dose-dependent manner.
结果：APN对AD P诱导血小板聚集有剂量依赖性抑制作用。
Results Nitric oxide was directly toxic to PC12 cells in a dose-dependent manner, and brain tissue homogenate extracts taken from hypoxia preconditioned mice could prevent PC12 cells from NO toxicity.
结果NO对PC12细胞可以产生剂量依赖性的直接毒性作用，而缺氧预适应小鼠脑匀浆提取液能有效对抗NO神经毒性作用。
Results Nitric oxide was directly toxic to PC12 cells in a dose-dependent manner, and brain tissue homogenate extracts taken from hypoxia preconditioned mice could prevent PC12 cells from NO toxicity.
结果NO对PC12细胞可以产生剂量依赖性的直接毒性作用，而缺氧预适应小鼠脑匀浆提取液能有效对抗NO神经毒性作用。
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