All the effects were in a time and dose dependent manner.
上述作用均呈时间和剂量依赖性。
Results: (1) There was dose dependent effect of zinc on the neuron survival.
结果(1)锌促进神经细胞的存活作用具有剂量效应关系。
The fracture risk is dose dependent and occurs rapidly after the start of treatment.
这种骨折是剂量依赖性的，并且在治疗开始后很快发生。
Aspirin could rescue Y79 cells from hyperthermia induced apoptosis in a dose dependent manner.
阿斯匹林可抑制热诱导的Y79细胞的凋亡，也呈剂量依赖性。
Pharmacodynamic assay has shown that inhibition of proteasome is dose dependent and reversible.
药效学分析表明蛋白酶体抑制药的抑制作用有剂量依赖性和可逆性。
The inhibition of JSL to the amplitude and frequency of gastric myoelectric activity was dose dependent.
静松灵对犬胃肌电频率和振幅的影响有剂量相关性；
ATRA could induce morphological differentiation and inhibit growth of SY5Y cells and showed time and dose dependent manner.
ATRA对SY5Y细胞有抗增殖作用和诱导细胞分化作用，并呈一定时间和剂量依赖关系。
Results Venenum Bufonis had growth inhibitory and apoptosis-inducing effects on U2OS cell with a time and dose dependent relation.
结果蟾酥水提取物对U2 OS细胞具有生长抑制及诱导凋亡作用，且呈时间依赖和剂量依赖。
Inflammatory changes including neutrophil and monocyte, lymphocyte hyperplasia were observed on pulmonary pathological slide in a dose dependent.
肺组织病理切片有炎性改变，单核细胞和中性粒细胞浸润和淋巴细胞增生，有剂量效应关系。
Results IL 6 up regulated the expression of CD14 and down regulated the expression of SR in a time and dose dependent fashion at the level of mRNA.
结果在基因转录水平，IL6对CD14表达呈时间剂量依赖性上调，对SR的表达呈进行性下调；
Conclusion progesterone was involved directly in osteocalcin production by regulating gene expression and this effect of progesterone was time and dose dependent.
结论孕酮从基因水平调节离体胎鼠成骨细胞骨钙素的生成，这种调节呈现时间及剂量依赖。
CONCLUSION Acetazolamide decreased the osmotic water permeability induced by AQP1 and inhibited the water transporting function of AQP1 in a dose dependent manner.
结论乙酰唑胺剂量依赖性地降低AQP1介导的渗透水通透性，抑制AQP1转运水的功能。
Results The result of LDH leakage showed that indomethacin could induce the injury of RGM-1 in a dose dependent manner and LPS could lessen it significantly (P<0.05).
结果低浓度的吲哚美辛即可引起RGM-1细胞受损并且呈量效关系，LPS可以明显减轻这一作用（P<0.05）；
Conclusions m s protects gastric mucosa with dose dependent effect and the mechanism of action is relevant with its antioxidative capability and increase of mucus on the stomach surface.
结论MS保护胃黏膜的作用呈剂量依赖性，其作用机制与抗氧化和促进胃黏膜黏液生成有关。
For instance, research published in the October 2006 issue of the FASEB Journal shows that aspirin, through different mechanisms, also has a dose dependent relationship for heart disease and cancer.
例如，发表在2006年10月的《美国实验生物学学会联合会》杂志的研究显示：通过不同机构生产的阿司匹林对心脏病和癌症的治疗作用同样与剂量有关系。
Mice received different doses of the extract, with a dose-dependent decrease in HE tumour size recorded, in addition to “significantly enhanced survival”, said the researchers.
研究人员称：“老鼠接受不同剂量的提取物后，HE 肿瘤大小在记录中呈剂量依赖性下降，此外，还能显著提高生存率。”
And it was dose-dependent - that is, the more chocolate consumed, the lower the risk for death.
这与巧克力摄入量有关，也就是说，吃的巧克力越多，发病死亡率越小。
For instance, research published in the October 2006 issue of the FASEB Journal shows that aspirin, through different mechanisms, also has a dose-dependent relationship for heart disease and cancer.
例如，发表在2006年10月的《美国实验生物学学会联合会》杂志的研究显示：通过不同机构生产的阿司匹林对心脏病和癌症的治疗作用同样与剂量有关系。
Although the reduction in trophoblast cell viability induced by PDG was dose-dependent Fig. 2, no such effect could be detected following treatment with LPS at varying concentrations Fig. 2c.
PD G减少滋养层细胞活力的作用是呈剂量依赖性的如图2，但以不同浓度的LPS处理细胞时，我们并未发现其有减少细胞活力的作用。
The effect of the hormone was time and dose-dependent.
激素的作用呈时间及剂量依赖性。
Leptin administration led to increased proliferation of rat NP cells in a dose-dependent manner, as shown by MTT assay and by counting the percentage of PCNA-positive cells.
正如MTT法和计数pcna阳性细胞比例所显示：瘦素的给予与鼠np细胞的增殖成剂量依赖性关系。
Microcystins can interfere with the development of embryos, delay hatching time, reduce hatchability and increase malformation rate with a dose-dependent manner.
微囊藻毒素能干扰鱼类胚胎发育，延迟出膜时间，降低孵化率，增加畸形率，而且还具有剂量依赖效应。
Bleomyin, an anti - neoplastic agent, is well known to induce- dose - dependent lung injury and pulmonary fibrosis in both humans and animals.
博莱霉素是一种抗肿瘤药物，普遍认为在人体和动物模型内均可产生剂量依赖型的肺损伤和肺纤维化。
The results showed that SM increased the blood flow of brain and cerebral cortex in a dose-dependent manner and had no effect on the blood flow of femoral arteries.
结果表明，桑葛合剂可以明显增加兔脑及大脑皮层的血流量，且呈剂量依赖性，但对股动脉血流量则无明显影响；
Results Nitric oxide was directly toxic to PC12 cells in a dose-dependent manner, and brain tissue homogenate extracts taken from hypoxia preconditioned mice could prevent PC12 cells from NO toxicity.
结果NO对PC12细胞可以产生剂量依赖性的直接毒性作用，而缺氧预适应小鼠脑匀浆提取液能有效对抗NO神经毒性作用。
Results: Paclitaxel inhibited the growth of A375 cells by inducing apoptosis in a both time-dependent and dose-dependent manner(P<0.01).
结果：紫杉醇通过诱导细胞凋亡抑制A375细胞生长，并呈时间和剂量依赖性（P<0.01）；
Results HDI could inhibit the proliferation of SPC-A-1 cells and inhibitory effect was dose-dependent.
结果白花蛇舌草注射液能抑制SPC-A-1细胞增殖，且呈剂量依赖性；
Conclusion CTX SO3 could inhibit the CNS of mice and cause a dose-dependent tremor, which may be related to the central 5-ht system.
结论芋螺毒素so3对小鼠神经系统有一定抑制作用，同时伴有剂量依赖性震颤，其机制可能与中枢5 -羟色胺系统有关。
DWN potently inhibited both decrease of SOD and PGE2 and increase of MDA in damaged gastric mucosa induced by ethanol in a dose-dependent manner.
胆胃宁尚可有效抑制乙醇损伤胃黏膜所致的SOD和PGE2降低以及MDA升高，且具有剂量依赖性。
DWN potently inhibited both decrease of SOD and PGE2 and increase of MDA in damaged gastric mucosa induced by ethanol in a dose-dependent manner.
胆胃宁尚可有效抑制乙醇损伤胃黏膜所致的SOD和PGE2降低以及MDA升高，且具有剂量依赖性。
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