• It has been reported that some human and mouse serum DNA-binding proteins were related to tumor.

    血清dna结合蛋白质中的某些成分与肿瘤有关。

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  • Classification of TF families has been improved by adopting a new DNA-binding domain nomenclature.

    TF家族的分类通过采用一个新的DNA结合区域命名法被改进。

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  • Recently, the traditional DNA-binding protein HMGB1 was discovered as a potent proinflammatory cytokine.

    近年来发现高迁移率族蛋白B1(HMGB1)这一传统DNA结合蛋白是强大的致炎细胞因子。

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  • Objective The specific property for DNA-binding of human telomerase was tested by gel mobility shift assay.

    目的采用凝胶迁移阻滞法分析研究人类端粒酶dna结合特性。

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  • MYBS3 is a single DNA-binding repeat MYB transcription factor previously shown to mediate sugar signaling in rice.

    MYBS 3是含有单个dna结合重复序列的MY B转录因子,之前的研究表明MY BS 3介导水稻的蔗糖信号传导。

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  • Transcription factors were grouped into different families according to the type of DNA-binding domain that they encode.

    根据与DNA结合的区域不同,转录因子分为若干个家族。

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  • The M domain, which encodes the DNA-binding domain and plays the roles of both binding DNA and forming dimmers, is the most conserved region.

    其中M区高度保守,它编码真核生物转录因子的DNA结合域,具有DNA结合和二聚体形成的作用。

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  • The M domain, which encodes the DNA-binding sequence and plays the roles of both binding DNA and forming dimmers, is the most conserved region.

    其中M区高度保守,它编码真核生物转录因子的DNA结合域,具有DNA结合和二聚体形成的作用。

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  • The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).

    这两种酶是组蛋白乙酰转移酶(它能给蛋白质添加乙酰基)和甲基化dna结合蛋白- 2(它能把DNA上的甲基去除)。

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  • While heat shock promoted the phosphorylation and nuclear translocation of HSF1, the ability of this nucleus-localized HSF1 to form the DNA-binding trimer was reduced.

    HSF1的亚细胞定位分析显示,HSF1主要存在于年轻细胞胞质中,热刺激促使三体形成和核转移;

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  • Zinc finger nucleases (ZFNs) are artificial restriction enzymes made by fusing an engineered zinc finger DNA-binding domain to the DNA cleavage domain of a restriction enzyme.

    锌指核酸酶是一种人工制做限制性内切酶,通过将锌指DNA结合区与限制性内切酶的DNA切割区融合获得。

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  • This research will facilitate to find new DNA-binding protein, and it is important to reveal the molecular mechanisms of DNA replication and transcription and DNA repair and recombination.

    该研究对于寻找新的DNA结合蛋白,研究生物体中遗传信息的复制、转录、修复和重组的分子生物学机制具有重要意义。

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  • This review summarizes recent advances in this field, and the relationship between sequence-specific DNA-binding transcription factors and their roles in recruitment of chromatin remodeling enzymes.

    本文综述了在这一领域的最新进展,以及序列特异性DNA结合转录因子和染色质重塑酶在招聘自己的角色之间的关系。

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  • The compounds show absorption hypochromicity, fluorescence enhancement, DNA melting increasement when binding to CT·DNA.

    结果显示,混配配合物与DNA 作用时,使紫外吸收明显减色,荧光显著增强,DNA熔点升高。

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  • CREB DNA binding activity of tested animals at different developing time was higher than that in control groups.

    实验组大鼠幼仔小脑CREBDNA结合活性均高于相应对照组。

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  • AIM to explore the changes in the activation of signal transducer and activator of transcription-3 STAT3 and DNA binding activation in facial nerve nucleus after facial nerve injury and repair.

    目的:探讨面神经损伤与修复条件下,面神经核运动神经元信号转导子和转录激活子3的活性以及DNA结合活性的变化。

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  • This score enables ranking of different DNA binding sites given a protein binding site and vice versa and can be used in molecular design protocols.

    这评分使排名不同的DNA结合位点提供的蛋白质结合位点,反之亦然,可以用于分子设计议定书。

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  • Methods: DNA damage was measured by the loss of fluorescence after DNA binding to ethidium bromide and by the increased DNA mobility in agarose gel electrophoresis.

    方法:通过DNA结合溴乙锭后的荧光损失和DNA琼脂糖凝胶电泳的迁移率来测定dna的损伤程度。

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  • To improve a gel retardation Assay for the study of binding in the nuclear protein and DNA.

    目的:探讨改良的凝胶阻滞法用于核蛋白-DNA结合的检测。

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  • DNA binding domains that are elongated, with a shape that is somewhat like a finger. The shape of the domain is coordinated by one or more zinc atoms.

    伸展的、形状有些像手指的DNA结合域。这一形状由一个或多个锌原子进行协调。

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  • The results showed that the DNA binding activity of NFAT gradually decreased , with trough value of NFAT binding activity , accounting for 41% of the control, observed at 4d after injury.

    结果显示,创伤后脾细胞NFAT的DNA结合活性逐渐下降,至伤后4天时下降最明显,仅为正常对照组的41%。

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  • Conclusion: the method was suitable for screening the anti tumor active ingredients of medicinal plant which contains DNA binding substances to take place of other complicated and dear cost method.

    结论:本测定方法可用来检测能与DNA作用的抗肿瘤活性成分,以替代复杂而昂贵的生物实验方法。

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  • EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).

    EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子,它可以EGR响应元素(ER),调节靶基因的表达(1)。

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  • Within the known classes of DNA binding proteins, the zinc finger is the greatest family and are nature′s most successful designs for DNA?binding proteins.

    锌指是最大的DNA结合蛋白家族,是识别DNA最有效、最成功的一种结构元件。

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  • The functional expression of DNA binding domain of Zif268 will greatly facilitate the development of in vivo genetic selection assay for the study of Zinc fingers-DNA interaction.

    锌指DNA结合区在大肠杆菌中的功能性表达成功为锌指蛋白DNA相互作用的胞内遗传筛选模型的建立奠定了基础。

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  • By serially introducing droplets containing sample or reagents, DNA Binding, magnetic beads rinsing, DNA elution and PCR were performed in the capillary.

    顺序向毛细管中引入含有不同试样的液滴,完成进样、DNA结合、洗涤、洗脱,扩增等过程。

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  • No open reading frame encoding TNP1/TNPA-like DNA binding protein were found in this element.

    该因子没有能够编码类似TNP1/TNPA的DNA结合蛋白的开读框。

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  • The yeast three-hybrid have three components: a protein fused with DNA binding domain, a hybrid RNA molecule, a protein fused with DNA activation domain.

    酵母三杂交系统由三部分组成:DNA结合结构域融合蛋白、杂交RNA分子、DNA激活结构域融合蛋白。

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  • Methods: receptor radioligand binding assay, receptor DNA binding assay and immunofluorescence methods were used.

    方法:采用受体放射配基结合分析、受体- DNA结合分析及免疫荧光技术。

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  • Methods: receptor radioligand binding assay, receptor DNA binding assay and immunofluorescence methods were used.

    方法:采用受体放射配基结合分析、受体- DNA结合分析及免疫荧光技术。

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