• Dihydrolipoamide succinyltransferase (DLST) is a key subunit in this complex (2).

    二氢硫辛酰胺-琥珀酰转移酶是复合物中的关键亚基(2)。

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  • Mutations in the DLST gene may be responsible for the familial Alzheimer disease (1).

    该基因的突变会导致家族性的阿尔茨海默病(1)。

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  • Reduction of DLST increases the generation of reactive oxygen species production suggesting its role in oxidative stress (2).

    DLST的数值减少会增加活性氧簇的产生,提示它可能在氧化应激中发挥作用(2)。

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  • Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro188 of human DLST protein.

    该单克隆抗体是由合成的人源dlst蛋白脯氨酸(188位)肽段免疫动物而制备的。

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  • Deficiency of DLST in mice was suggested to cause increased oxidative stress in mitochondria and is involved in the pathogenesis of Alzheimer disease (2).

    DLST缺失小鼠线粒体氧化应激增加,并且会导致阿尔茨海默病的发生(2)。

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  • Research has shown that deficiency of DLST in mice is linked to increased oxidative stress in mitochondria, a process that may be involved in the pathogenesis of Alzheimer's disease (2).

    研究表明,小鼠中DLST缺失与线粒体氧化应激的增加有关,并且会出现阿尔茨海默病的病理现象(2)。

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  • Research has shown that deficiency of DLST in mice is linked to increased oxidative stress in mitochondria, a process that may be involved in the pathogenesis of Alzheimer's disease (2).

    研究表明,小鼠中DLST缺失与线粒体氧化应激的增加有关,并且会出现阿尔茨海默病的病理现象(2)。

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