The goal of this unit is to introduce gene-gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes.
这一单元的目的是介绍基因-基因相互作用(上位性)作为疾病易患基因研究中的一个显著的并发因素。
It is now known that genetic variability accounts for 25% of susceptibility to the disease, but that variations in the sickle-cell gene contribute to only a fraction of that.
现在，25 %的对疾病的敏感性被归咎于遗传变异。但在镰细胞基因上的变异仅仅参与了其中的一小部分。
Conclusions These results may provide clues to reveal the susceptibility gene of vitiligo in China and as well as the immunogenetic mechanisms of the disease.
结论该结果为进一步揭示白癜风的易感基因及免疫遗传发病机制提供了线索。
A gene polymorphism and susceptibility to disease and disease phenotype correlation there is the gene directly involved in the pathogenesis of corroboration.
而一个基因的多态性与疾病易感性及疾病表型都存在关联，是该基因直接参与发病的佐证。
These findings from the Genetic Epidemiology of Parkinson's Disease study suggest that the gene may impact susceptibility for Parkinson's disease and modify age at onset, the researchers said.
这些来自帕金森遗传病研究所的研究表明，基因可能影响得帕金森病的敏感性和发病年龄。
Chromatin modifications in response to extracellular cues, including during early life, regulate metabolic gene expression and may contribute to metabolic disease susceptibility.
包括新生时期在内的胞外信号会影响染色体的修饰，从而调控和代谢相关的基因表达，进而影响到我们代谢综合征的易感性。
Chromatin modifications in response to extracellular cues, including during early life, regulate metabolic gene expression and may contribute to metabolic disease susceptibility.
包括新生时期在内的胞外信号会影响染色体的修饰，从而调控和代谢相关的基因表达，进而影响到我们代谢综合征的易感性。
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