Results the DHPLC find the exon 7, 9 polymorphism.
结果:变性高效液相色谱检测出7、9号外显子多态性。
Fig 3 Atlas of concordant results between DHPLC and direct sequencing. The arrows indicated the mutant peaks.
图3DHPLC与直接测序结果相符的检测图谱,箭头提示突变峰。
Screening the mutations and polymorphisms by denaturing high-performance liquid chromatography(DHPLC) and DNA sequencing Results: 1.
应用变性高效液相色谱(DHPLC)分析及直接基因测序筛查突变和多态。
CONCLUSION: We first amplified mtDNA in circulating plasma from breast cancer patients by direct PCR, checked mutation by DHPLC and confirmed results by sequencing.
结论:本实验直接用PCR扩增乳腺癌血浆核酸中线粒体基因,并用DHPLC初步筛选突变并测序证实。
Objective to detect the ABL point mutations in chronic myeloid leukemia (CML) patients treated with imatinib by denaturing high-performance liquid chromatography (DHPLC).
目的应用变性高效液相色谱(DHPLC)检测伊马替尼治疗后慢性髓性白血病(CML)患者ABL激酶区点突变。
Objective to detect the ABL point mutations in chronic myeloid leukemia (CML) patients treated with imatinib by denaturing high-performance liquid chromatography (DHPLC).
目的应用变性高效液相色谱(DHPLC)检测伊马替尼治疗后慢性髓性白血病(CML)患者ABL激酶区点突变。
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