After birth, desmin expression was mainly concentrated in the Z lines of I bands and intercalated disks.
出生后,结蛋白表达主要集中于明带Z线和闰盘。
Scar tissue was seen in the control group, and desmin was negative and Troponin I was positive in cardiomyocytes.
对照组心脏标本中可见瘢痕组织;心肌细胞结蛋白染色阴性,肌钙蛋白i染色阳性。
The immunohistochemical method results showed positive reaction of part of the cell plasm desmin, myocardium specific troponin and connexin-43 after induction.
部分诱导后的细胞胞浆结蛋白,心肌特异性肌钙蛋白,连接蛋白- 43免疫组化呈阳性反应。
Indirect immunofluorescence detection showed that positive reaction of diffuse cytoplasmic fluorescence was seen with antibody to keratin but not with antibodies to vimentin and desmin.
间接免疫荧光染色显示,小鼠早期胚胎细胞对角蛋白抗体呈阳性反应,对波形蛋白和结蛋白抗体呈阴性反应。
Conclusion in myocarditis, expression of connexin 43 and desmin in the involved cardiac muscle cells was inhibited, resulting in dysfunction of gap junctional communication and arrhythmia.
结论病毒性心肌炎时受累的心肌细胞连接蛋白43和结蛋白的表达受到抑制,可能是导致心肌细胞缝隙连接通讯和收缩功能障碍以致心律失常的一个原因。
CONCLUSION: in myocarditis, expression of connexin 43 and desmin in the involved cardiac muscle cells was inhibited, resulting in dysfunction of gap junctional communication and arrhythmia.
结论:在心肌炎,连接蛋白43和结蛋白表达的参与心肌细胞受到抑制,在间隙连接通讯功能障碍引起的心律失常。
Results In normal mice, connexin 43 and desmin are located in the intercalated disks of cardiac muscle, and the latter also revealed a positive immunoreactivity in the cross striations of sarcomeres.
结果连接蛋白43和结蛋白在正常小鼠心肌闰盘中定位分布,均匀存在,后者还在肌节横纹中显示阳性;
Results In normal mice, connexin 43 and desmin are located in the intercalated disks of cardiac muscle, and the latter also revealed a positive immunoreactivity in the cross striations of sarcomeres.
结果连接蛋白43和结蛋白在正常小鼠心肌闰盘中定位分布,均匀存在,后者还在肌节横纹中显示阳性;
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