Objective:To analyze the curative effect on cerebral infarction with defibrase.
目的：探讨降纤酶治疗急性脑梗死的疗效。
Methods40 patients with acute ischemic stroke were treated by defibrase and the change of hemorheology was recorded before and after the treatment respectively.
方法应用降纤酶治疗40名脑梗死患者，分别记录治疗前后血液流变学的变化。
Results: The neurological function of the patients treated with defibrase was significantly improved, the scores of daily living abilities increased, and the level of fibrinogen in blood decreased.
结果：去纤酶组显著改善神经功能缺失程度，提高日常生活能力，降低血纤维蛋白原水平；
Defibrase can effectively reduce blood viscosity, content of fibrinogen, hemocyte aggregation and platelet aggregation.
降纤酶有明显降低血黏度、纤维蛋白原含量、红细胞聚集性、血小板聚集作用。
Conclusion: Defibrase can significantly decrease fibrinogen, improve whole blood viscosity, and decrease disability rate. With little side effect, it is effective on acute cerebral infarction.
结论：降纤酶治疗急性脑梗死疗效确切，能显著降低纤维蛋白原，改善全血黏度，降低致残率，不良反应少。
Conclusion: Defibrase can significantly decrease fibrinogen, improve whole blood viscosity, and decrease disability rate. With little side effect, it is effective on acute cerebral infarction.
结论：降纤酶治疗急性脑梗死疗效确切，能显著降低纤维蛋白原，改善全血黏度，降低致残率，不良反应少。
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