• The results indicate that the activity of CYP2E1 is markedly inhibited by florfenicol.

    提示,氟苯尼考对鲫鱼CYP2E1具有显著的抑制作用。

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  • Conclusion:ACR changes spermatogenesis in male rats, but not via the pathway of CYP2E1.

    结论:ACR可引起大鼠生精功能的改变,但未观察到CYP2E1在这种改变中的明显作用。

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  • These results suggested that FM has an inhibition effect on CYP3A4 and an induction effect on CYP2E1 in pigs.

    说明氟尼辛葡甲铵对猪的CYP3A4具有抑制作用,而对CYP2E1存在诱导效应。

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  • People who carry the version of the CYP2E1 gene linked to increased sensitivity to alcohol produce more of the enzyme.

    携带该CYP2E1类型基因的人增加了对酒精的敏感,产生更多的酶。

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  • This revealed that CYP2E1 on chromosome 10 appears to dictate whether a person can hold their drink better than others.

    这剖明,10号染色体上的CYP2E1基因似乎可以抉择一小我能否在喝酒时比别人默示得更好。

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  • CYP2E1 levels may be associated with human susceptibility to toxicity and carcinogenicity of industrial and environmental chemicals.

    CYP2E1表达水平可能是机体对环境和工业毒物或致癌物敏感程度的重要因素。

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  • To evaluate the relationship among polymorphism with CYP2E1 gene, habit of smoking and alcohol, and their interaction on the risk of esophageal cancer.

    目的:研究CYP2E1基因多态性和烟酒嗜好的相互作用,以及其与食管癌易感性的关系。

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  • QU exhibited competitive inhibition of CYP3A2 dextromethorphan N-demethylation reaction and expressed noncompetitive inhibition of CYP2E1 chlorzoxazone-6-hydroxylation reaction.

    槲皮素竞争性抑制CYP3A2右美沙芬N脱甲基反应,非竞争性抑制CYP2E1氯唑沙宗6羟化反应。

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  • Objective To study the relationship of genetic polymorphisms of cytochrome P4502E1(CYP2E1) and glutathione S-transferase M1(GSTM1) with genetic susceptibility of aplastic anemia(AA).

    目的探讨CYP2E1和GSTM1基因多态性与再生障碍性贫血(简称再障)遗传易感性的关系。

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  • The CYP2E1 enzyme works in the brain, which is not the major player in alcohol metabolism, says Wilhelmsen, a genetics professor at the University of North Carolina-Chapel Hill School of Medicine.

    北卡大学教堂山医学院的基因教授介绍说,WilhelmsenCYP2E1酶在大脑中工作,而这并不是酒精代谢的主要地方。

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  • Conclusion Chronic intermittent hypoxia can increase rat liver microsomal ERD and ANH activities. The mechanism is related to up-regulation of CYP3A2 and CYP2E1 expression at the transcriptive levels.

    结论慢性间断性低氧能明显增加大鼠肝脏erd (CYP3A2)和ANH (CYP2E1)活性,其机制可能与其在转录水平上提高肝脏cyp3a2和CYP2E1的基因表达水平有关。

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  • Conclusion Chronic intermittent hypoxia can increase rat liver microsomal ERD and ANH activities. The mechanism is related to up-regulation of CYP3A2 and CYP2E1 expression at the transcriptive levels.

    结论慢性间断性低氧能明显增加大鼠肝脏erd (CYP3A2)和ANH (CYP2E1)活性,其机制可能与其在转录水平上提高肝脏cyp3a2和CYP2E1的基因表达水平有关。

    youdao

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