Dextromethorphan metabolic phenotyping provides a new information for debrisoquine 4-hydroxylase (CYP2D6) polymorphism in native Chinese.
右美沙芬的代谢表型研究为中国本地人的异丁喹4-羟化酶（CYP2D6）多态性提供了新的信息。
Conclusion Sodium Ozagrel can induce the activity of CYP2D6.
结论奥扎格雷钠可诱导CYP2D6酶的活性。
In the present article, genetic polymorphism of CYP2D6 and its clinical implications were reviewed.
本文综述了CYP2D6在遗传多态性方面的研究进展及其临床意义。
For fluoxetine and paroxetine, dosage cutting is needed in case of coadministration with CYP2D6 substrates.
与治疗窗较窄的CYP2D 6底物合用时，应注意帕罗西汀和氟西汀的剂量调整。
It is feasible to explain CYP2D6 mutation-induced the reduction in the activity of enzymes by bioinformatics.
应用生物信息学方法对CYP2D6基因突变致使的酶活性的下降做出一些可能的解释是可行的。
Meanwhile, many drugs can influence the activity of CYP2D6 by competitive inhibition or induction, which is easy to cause interaction in coadministration.
而且CYP2D6能被多种药物竞争性抑制和诱导，药物联用时易产生相互作用。
So far, the biological features of CYP2D6 have been basically defined, which will be helpful to the further study on CYP2D6 and therefore to the rational drug usage.
目前，CYP2D6的生物学特征已被基本确定，这将十分有助于对CYP2D6的深入研究，从而为临床合理用药提供科学依据。
In the Present article, the characterization, substrates, probe drugs, factors affecting its activity, genetic polymorphism and the relation between CYP2D6 and several diseases were reviewed.
本文综述了CYP2D6的结构特点，底物，探针药物，影响其活性的因素，基因多态性以及它与疾病的关系。
In the Present article, the characterization, substrates, probe drugs, factors affecting its activity, genetic polymorphism and the relation between CYP2D6 and several diseases were reviewed.
本文综述了CYP2D6的结构特点，底物，探针药物，影响其活性的因素，基因多态性以及它与疾病的关系。
应用推荐