Deletion and mutation of CTCF is associated with cancer.
CTCF的缺失和突变可能导致肿瘤的发生。
We further show that CTCF binding to CD45 exon 5 is inhibited by DNA methylation, leading to reciprocal effects on exon 5 inclusion.
进一步的研究表明CD 45的外显子5与CTCF的结合受到DNA甲基化抑制，从而导致第5外显子包含的相互影响。
Of the 52 somatic nonsynonymous mutations found in 32 genes they found two genes involved in histone modification (CREBBP and CTCF).
他们在32个基因的52个体细胞非同义突变中找到了2个参与组蛋白修饰 （CREBBP 与 CTCF）的基因。
Objective: CTCF is a multifunctional transcription factor, which plays many roles in promoter regulation, insulator function and genetic imprinting.
目的：CTCF是一种多功能的转录因子，参与启动子调控、绝缘子功能和遗传印记等过程。
The molecule at the heart of the lock-and-key mechanism is a protein called CTCF, say the scientists in a paper published in the journal Genome Research.
科学家发表在《基因组研究》杂志的文章说，锁钥机制的核心分子是一个叫做CTCF的蛋白。
The molecule at the heart of the lock-and-key mechanism is a protein called CTCF, say the scientists in a paper published in the journal Genome Research.
科学家发表在《基因组研究》杂志的文章说，锁钥机制的核心分子是一个叫做CTCF的蛋白。
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