Therefore, deficiency of costimulatory molecules on tumor cells is one of the important mechanisms of tumor immune escape.
可见，肿瘤细胞上共刺激分子缺陷是肿瘤免疫逃逸的重要机制之一。
It has been showed that the expressions of costimulatory molecules are associated with xero organ transplantation rejection.
已有研究表明，共刺激分子的表达与同种异体移植排斥反应有关。
A crucial role in eliciting anti-tumor immunity of costimulatory molecule CD80 (B7-1) has been demonstrated by animal experimental studies.
动物实验证实协同刺激分子CD 80 (B7 - 1)是促进抗肿瘤免疫应答的重要分子。
CD47 induces costimulatory signals on activation of T cell, T cell apoptosis and T cell anergy and enhances the efficiency of TCR signaling;
CD4 7是T细胞活化的共刺激因子，活化T细胞凋亡过程，诱导T细胞无反应性，加强TCR信号传导的效率；
TLR2 is reported to enhance the expression of costimulatory molecules on the antigen presenting cell, however the regulatory mechanisms are still unclear.
已知tlr 2活化会促进抗原呈现细胞表面共同刺激分子的表现，但其调控机制及讯息传递路径仍不是非常清楚。
Objective Recent experimental data indicate that the costimulatory signal pathways of CD28 B7 and CD40 CD154 offer essential roles for t cell activation and effecting.
目的最新实验数据显示了CD 2 8 B7和CD 40 CD 15 4共刺激信号通路在T细胞活化与效应过程中起重要作用。
CONCLUSIONS: The whole blood gene expression quantities of costimulatory molecules CD154 and ICOS reasonably robustly differentiated rejection patients from control patients.
结论：共刺激分子CD 154和ICOS的全血基因表达量能可靠的区分排异患者和对照患者。
Additionally, research efforts should continue to identify and manipulate new costimulatory targets and immunosuppressants, which may be key to abrogating memory T-cell responses.
另外，科研人员应继续开发和利用新型共刺激靶点及免疫抑制剂，这可能对消除记忆性T细胞的反应有关键作用。
Objective: to explore the expression characteristics of intracellular cytokines and surface costimulatory molecules in embryo antigen tolerant t cells transferred in pregnant mice.
目的：分析过继转输的小鼠胚胎抗原耐受T细胞内细胞因子及细胞表面协同刺激分子的表达特征。
Objective to explore the significance of costimulatory molecule B7-1 (CD80) and MHC molecules in the pathogenesis of hematologic malignant tumors and in the immuno-genetic therapy.
目的探讨共刺激分子B7 1 (CD80)在血液系统恶性肿瘤发病学及免疫基因治疗中的重要作用。
Objective to explore the significance of costimulatory molecule B7-1 (CD80) and MHC molecules in the pathogenesis of hematologic malignant tumors and in the immuno-genetic therapy.
目的探讨共刺激分子B7 1 (CD80)在血液系统恶性肿瘤发病学及免疫基因治疗中的重要作用。
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