OBJECTIVE To select the in vitro release medium for elevating the colon-specific effect of preparations prepared with konjac glucomannan.
目的筛选合适的释放介质，用于魔芋胶为载体结肠定位给药系统的体外评价。
CONCLUSION: the molecular mass of dextran has great influence on the drug release of conjugates in vitro. PLD2 and PLD50 have potentials in colon specific delivery of prednisolone.
结论：葡聚糖分子质量对强的松龙葡聚糖连接物的体外释药有明显影响，PLD 2,PLD5 0具有结肠定位释放潜力。
CONCLUSION The sustained-release and colon-specific characteristics of metronidazole colon-specific sustained-release tablets were obvious.
结论甲硝唑结肠缓释片具有结肠靶向和缓释的特征。
CONCLUSION The sustained-release and colon-specific characteristics of metronidazole colon-specific sustained-release tablets were obvious.
结论甲硝唑结肠缓释片具有结肠靶向和缓释的特征。
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