Patients with classic PMD present in infancy with nystagmus, spasticity, and other motor problems.
经典型PMD病人在婴儿期表现为眼球震颤、痉挛和其他的运动问题。
In classic PMD, the MRI findings tend to be stable or mildly progressive over years since the primary problem is hypomyelination rather than demyelination.
在经典型PMD中，MRI异常改变在多年后都保持稳定或仅有轻微的进展，这是因为其病因在于髓鞘形成不良而不是脱髓鞘。
The classic "tigroid" appearance that is the result of heterogeneous areas of myelination and dysmyelination may be seen on MRI but this finding is not exclusive to PMD.
典型的虎斑状改变是由于正常髓鞘形成的区域和髓鞘形成不良的区域交杂在一起所致，可以在MRI上看到，但是这种改变并不是PMD独有的。
The classic "tigroid" appearance that is the result of heterogeneous areas of myelination and dysmyelination may be seen on MRI but this finding is not exclusive to PMD.
典型的虎斑状改变是由于正常髓鞘形成的区域和髓鞘形成不良的区域交杂在一起所致，可以在MRI上看到，但是这种改变并不是PMD独有的。
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