Summary of Background Data. Recently we described an IVD degeneration model in the goat by injecting chondroitinase ABC. This results in mild progressive disc degeneration.
背景资料分析： 先前我们已经发表了通过注射软骨素酶ABC建立山羊IVD退变模型的研究。这种实验方法可导致间盘的轻度进行性退变。
Objective:To investigate the effects of chondroitinase ABC on chondroitin sulfate proteoglycans(CSPGs) and growth associated protein-43(GAP-43)after spinal cord injury in rats.
目的：探讨硫酸软骨素酶ABC对严重的大鼠脊髓损伤蛋白多糖及生长相关蛋白43（GAP-43）基因表达的影响。
Objective. Simulate the reduced glycosaminoglycan content and altered mechanics observed in intervertebral disc degeneration using a controlled injection of chondroitinase ABC (ChABC).
目的：模拟氨基葡聚糖含量减少模型以及通过适当的软骨素酶abc注射液来观察椎间盘退变发生气制。
Objective. Simulate the reduced glycosaminoglycan content and altered mechanics observed in intervertebral disc degeneration using a controlled injection of chondroitinase ABC (ChABC).
目的：模拟氨基葡聚糖含量减少模型以及通过适当的软骨素酶abc注射液来观察椎间盘退变发生气制。
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