Methods: MTT method for determition of CHL Cell IC 5 0, Salmonella mutagenicity test, and mouse acute toxicity test were used.
方法:CHL细胞采用MTT比色法,沙门氏菌诱变性试验和小鼠急性毒性试验。
The effect of arginine esterase (an effective component of ahylysantinfarctase) on CHL cell growth inhibition and chromosome aberration in vitro was studied.
试验结果表明,精氨酸酯酶在上述浓度对CHL细胞的增殖没有抑制作用,对CHL细胞的染色体结构也没有影响。
Objective To observe the effects of puerarin on the morphology, cell proliferation activity, and cell relative survival rate of Chinese hamster lung cells (CHL).
目的:观察葛根对中国仓鼠肺细胞(chl)形态学、细胞增殖活性及细胞相对存活率的影响。
Several studies have shown that SO2 and its derivatives could induce chromosomal aberrations, sister chromatid exchanges and micronuclei in human blood lymphocyte, bone marrow cell in mice and CHL.
研究发现,SO_2及其衍生物可引起人外周血淋巴细胞、小鼠骨髓细胞、中国仓鼠肺成纤维细胞等哺乳动物细胞的染色体畸变、姊妹染色单体交换及微核的形成。
Results It was proved that a CHL 3a4 transgenic cell line was established, which could lead metabolic activation for aflatoxin B1 (AFB1), sterigmatocystin (STC) and cyclophosphamide (CPA).
结果建立了CHL ?3a4转基因细胞系,双核细胞微核试验证明该细胞系能代谢活化黄曲霉毒素b 1 (afb1)、杂色霉菌毒素(STC)、环磷酰胺(CPA)。
AIM To establish a cell line CHL UDP glucuronosyltransferase gene (UDPGT1A9) which will stably express human UDPGT1A9 protein and determine the activity of expressed UDPGT1A9 in drug glucuronidation.
目的为建立能稳定表达人葡糖醛酸转移酶UDPGT1A9蛋白的CHL UDPGT1A9转基因细胞系,并鉴定其对药物的葡糖醛酸缀合活性。
AIM To establish a cell line CHL UDP glucuronosyltransferase gene (UDPGT1A9) which will stably express human UDPGT1A9 protein and determine the activity of expressed UDPGT1A9 in drug glucuronidation.
目的为建立能稳定表达人葡糖醛酸转移酶UDPGT1A9蛋白的CHL UDPGT1A9转基因细胞系,并鉴定其对药物的葡糖醛酸缀合活性。
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