• Methods: MTT method for determition of CHL Cell IC 5 0, Salmonella mutagenicity test, and mouse acute toxicity test were used.

    方法CHL细胞采用MTT比色法沙门氏菌诱变性试验小鼠急性毒性试验。

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  • The effect of arginine esterase (an effective component of ahylysantinfarctase) on CHL cell growth inhibition and chromosome aberration in vitro was studied.

    试验结果表明,精氨酸上述浓度对CHL细胞的增殖没有抑制作用CHL细胞的染色体结构也没有影响。

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  • Objective To observe the effects of puerarin on the morphology, cell proliferation activity, and cell relative survival rate of Chinese hamster lung cells (CHL).

    目的观察葛根中国仓鼠细胞(chl)形态学细胞增殖活性细胞相对存活率影响。

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  • Several studies have shown that SO2 and its derivatives could induce chromosomal aberrations, sister chromatid exchanges and micronuclei in human blood lymphocyte, bone marrow cell in mice and CHL.

    研究发现,SO_2及其衍生物引起外周血淋巴细胞、小鼠骨髓细胞、中国仓鼠肺成纤维细胞等哺乳动物细胞的染色体畸变姊妹染色单体交换微核的形成。

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  • Results It was proved that a CHL 3a4 transgenic cell line was established, which could lead metabolic activation for aflatoxin B1 (AFB1), sterigmatocystin (STC) and cyclophosphamide (CPA).

    结果建立CHL3a4转基因细胞系,双核细胞微核试验证明该细胞系代谢活化黄曲霉毒素b 1 (afb1)、杂色霉菌毒素(STC)、环磷酰胺(CPA)。

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  • AIM To establish a cell line CHL UDP glucuronosyltransferase gene (UDPGT1A9) which will stably express human UDPGT1A9 protein and determine the activity of expressed UDPGT1A9 in drug glucuronidation.

    目的建立稳定表达葡糖醛酸转移酶UDPGT1A9蛋白CHL UDPGT1A9转基因细胞系,并鉴定其对药物的葡糖醛酸缀合活性

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  • AIM To establish a cell line CHL UDP glucuronosyltransferase gene (UDPGT1A9) which will stably express human UDPGT1A9 protein and determine the activity of expressed UDPGT1A9 in drug glucuronidation.

    目的建立稳定表达葡糖醛酸转移酶UDPGT1A9蛋白CHL UDPGT1A9转基因细胞系,并鉴定其对药物的葡糖醛酸缀合活性

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