Chk2 is the mammalian orthologue of the budding yeast Rad53 and fission yeast Cds1 checkpoint kinases (1-3).
Chk2是哺乳动物中和芽殖酵母Rad53和裂殖酵母Cds1检验点激酶同源的蛋白（1-3）。
An important part of the cellular response to DNA damage is checkpoint activation - checkpoint kinases CHK1 and CHK2 phosphorylate key proteins to elicit cell-cycle blocks.
细胞对DNA损伤作出应答的一个重要过程是检查点活化(检查点激酶CHK1和CHK2使关键蛋白磷酸化，从而阻止正常的细胞周期。)
An important part of the cellular response to DNA damage is checkpoint activation - checkpoint kinases CHK1 and CHK2 phosphorylate key proteins to elicit cell-cycle blocks.
细胞对DNA损伤作出应答的一个重要过程是检查点活化(检查点激酶CHK1和CHK2使关键蛋白磷酸化，从而阻止正常的细胞周期。)
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