• The new US study of zebrafish has identified a key cellular pathway that appears to trigger regeneration by switching on certain genes.

    美国对斑马鱼的最新研究确认,再生的关键细胞途径似乎是通过开关某种基因而激活再生。

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  • We have designed a strategy to select new drug targets that inhibit a cellular gene required for HBV replication or restore a response stalled by HBV in the ATR DNA damage pathway.

    筛选新的药物靶点可以通过抑制HBV复制必需的一个基因或者保持HBV所引起的AT R损伤途径中的一种失调反应。

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  • Ubiquitin-proteasome pathway is an important mechanism regulating many processes of cellular biology, and also a potential target for abnormal regulation associated with malignancy.

    泛素蛋白酶体途径是调节多种细胞生物学过程的重要机制,也是恶性肿瘤相关调节异常的潜在靶点;

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  • Metabolic engineering is the analysis of metabolic pathway and designing rational genetic modification to optimize cellular properties by using principle of molecular biology.

    代谢工程是利用分子生物学原理系统分析代谢途径,设计合理的遗传修饰策略从而优化细胞的生物学特性。

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  • MAPK signaling transduction is a key pathway of cellular proliferation and apoptosis regulation.

    MAPK信号转导通路是一条关键的调节细胞增生和凋亡的通路。

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  • CONCLUSION: Acetaldehyde causes oxidative damage in cardiomyocytes through enhancing cellular ROS level, and induces cardiocytes apoptosis by activating ROS mediated JNK pathway.

    结论:乙醛通过增高胞内ros水平损伤心肌细胞,激活ros介导JNK途径诱导细胞凋亡。

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  • The established view in cellular biology dictates that the cellular internalization of hydrophilic macromolecules can only be achieved through the classical endocytosis pathway.

    传统细胞生物学的观点认为:亲水性大分子只能通过经典的胞吞作用才能实现细胞内在化。

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  • Conclusion: NTD embryos were induced by PMX, the mechanism of which might be PMX inhibited folate metabolism pathway and led to decreased cellular proliferation and excessive cellular apoptosis.

    结论:PM X能诱导NTD的发生,其机制可能是因为PMX阻断了叶酸代谢通路并导致神经上皮细胞的增殖抑制和过度凋亡。

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  • Protein degradation mediated by ubiquitin-proteasome pathway is an important mechanism which modulates cellular proteins′ activity and function.

    泛素- 蛋白酶体途径介导的蛋白降解是机体调节细胞内蛋白水平与功能的一个重要机制。

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  • Protein degradation mediated by ubiquitin-proteasome pathway is an important mechanism which modulates cellular proteins′ activity and function.

    泛素- 蛋白酶体途径介导的蛋白降解是机体调节细胞内蛋白水平与功能的一个重要机制。

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