Once the defense mechanism is shut off, mRNA carrying the genes for cell reprogramming can be safely delivered.
只要关闭了这种自卫机制，能够重新编码细胞且携带遗传基因的信使RNA就能安全导入了。
We are eager to explore the underlying transcriptional and epigenetic mechanisms of somatic cell reprogramming.
我们将研究在体细胞重编程过程中的转录调控和表观遗传调控机制。
In addition to helping with studies of stem cell reprogramming, this technique could be used to study interactions between any types of cells.
除了帮助研究干细胞基因遗传，这种技术可以用来研究任何类型的细胞之间的相互作用。
In the present paper we review the role and molecular mechanism of transcription factors, epigenetic regulation and cell signaling in cell reprogramming.
本文主要从转录因子、表观遗传和信号转导等角度，介绍了细胞重编程分子机制研究方面的进展和未来的方向。
Researching the mechanism of action of these transcription factors is beneficial to the further explanation of the molecular mechanism of the cell reprogramming.
对这些转录因子作用机制的了解，有助于细胞重编程分子机制的进一步阐明。
The researches of therapeutic cloning and somatic cell reprogramming, two strategies used to generate patient-specific autologous stem cells, have recently made great progress.
治疗性克隆和体细胞重编程是制备患者特异性自体干细胞的两种不同策略，近期已取得了重大的研究进展。
For reprogramming to be safe enough to use in cell therapy, researchers must find an efficient, reliable way to trigger it.
为了让细胞“重编程”在细胞疗法中变得足够安全，科学家们必须寻找一种高效且可靠的办法来激活它。
This switch exemplifies a type of genetic reprogramming that has been a source of debate and great interest in the world of stem cell research.
这一转换成为了一种基因重组的例证，并在干细胞研究领域引起了广泛的讨论。
The drug ACTS by essentially reprogramming the metabolism of cancer cells, re-teaching them to undergo apoptosis, or cell death.
它可以重组癌细胞的新陈代谢，重新教会癌细胞如何死亡。
The donor nucleus must experienced the epigenetic modification of the process reprogramming and went back to the initial state after the donor cell was injected into the oocytes.
供体细胞核移入去核的卵母细胞后，必定要经过表观遗传修饰的重编程过程，回到胚胎开始发育的全能状态。
In general idea, cumulus cell is the best nuclear donor cell for reprogramming.
一般来说，颗粒细胞作为核供体最易被核重编程。
The donor cell and recipient cytoplasm are main factors in the nuclear transfer reprogramming.
供体核和受体胞质是影响核移植重构胚重编程的主要因素。
However, nuclear reprogramming, which stands in the way of reconstructed embryo stem cell research, is still a bottleneck in the procedure of nuclear transfer.
但是核重编程仍是核移植技术的瓶颈，制约了重构胚胎干细胞的研究。
However, nuclear reprogramming, which stands in the way of reconstructed embryo stem cell research, is still a bottleneck in the procedure of nuclear transfer.
但是核重编程仍是核移植技术的瓶颈，制约了重构胚胎干细胞的研究。
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