The antigenicity of CD28 displayed on phage was detected by ELISA and FCM.
用ELISA和流式细胞仪检测展示在噬菌体上CD 28的抗原性。
Using this method, the reshaping anti CD28 single domain antibodies were constructed.
利用该方法构建了改形抗cd28重链单域抗体。
The reshaping anti-CD28 single domain antibodies were constructed by using this method.
利用该方法构建了改形抗CD28重链单域抗体。
Objective:To explore the effect of CD28 molecule on tumor immunity of mycosis fungoides (MF).
目的：探讨CD28分子在蕈样肉芽肿（MF）肿瘤免疫中的作用。
Objective To analyze CD8 and CD28 t - lymphocyte subgroups in patients with advanced malignancies.
目的分析晚期恶性肿瘤患者CD8及CD 28T淋巴细胞亚群的构成。
The correlation between the fraction of CD4+CD28-T cells and lymphocytic apoptosis was also observed.
分析CD4+CD28-T细胞比例与外周血淋巴细胞凋亡率的相关性。
Objective To analyze the expression levels of CD28 on the CD8 + lymphocytes from patients with multiple sclerosis (MS).
目的探讨CD2 8在多发性硬化（MS）患者CD8+淋巴细胞的表达水平。
Objective To study the effect of soybean isoflavones on CD28 T-cell expression level of and liver antioxidation level in aging rats.
目的研究大豆异黄酮对老龄大鼠t细胞CD 28表达水平及肝脏氧化应激水平的影响。
Methods the levels of CD28 of the patients of craniocerebral trauma before and after treatment were detected by flow cytometry (FCM).
方法采用流式细胞技术(FCM)用三色标记法检测脑损伤患者治疗前后CD 28的表达。
Conclusion CD8 + t lymphocytes increases in active stage of SLE, but most of them are CD8 + CD28 - t lymphocytes. They lost inhibitive activity.
结论SLE活动期患者虽然CD 8 +细胞增多，但大多数是CD 8 +CD 28-细胞，失去细胞毒性作用。
ObjectiveTo explore the biological features of spleen CD8 + CD28 - t cells from spontaneous tolerance models of rats with orthotopic liver transplantation.
目的研究近交系大鼠原位肝移植自发免疫耐受模型中cd 8 +CD 2 8-T抑制细胞的生物学特点。
To study the effect and mechanism of CD8+CD28-T cell on remote ischemic preconditioning protects the rat kidney from early warm ischemia-reperfusion injury.
目的探讨CD8+CD28-T细胞在远程缺血预处理保护早期肾脏热缺血再灌注损伤中的作用。
CD137 and CD28 can promote the activation and survival of t cells in aged and D-gal group. But CD28 has stronger effect on regulation of t cells than CD137.
CD 137及CD 28分子对两组衰老T细胞有近似的调节作用，均能促进衰老T细胞的活化及存活，CD 28分子的调节作用强于CD 137分子。
AIM: to investigate the fraction of CD4 + CD28-T cells and its correlation with lymphocytic apoptosis in peripheral blood of rheumatoid arthritis (ra) patients.
目的：研究类风湿关节炎(RA)患者外周血cd4 + CD 28 - T细胞比例与淋巴细胞凋亡异常的相关性。
CD80 is one of the co-stimulatory molecules binding CD28, which binds CD28 on the surface of t cells to provide second signal for efficient activation of t cells.
而CD 80是能够与CD 28分子结合的共刺激分子之一，它与T细胞表面CD 28分子的结合为T细胞有效活化提供第二信号。
Objective Recent experimental data indicate that the costimulatory signal pathways of CD28 B7 and CD40 CD154 offer essential roles for t cell activation and effecting.
目的最新实验数据显示了CD 2 8 B7和CD 40 CD 15 4共刺激信号通路在T细胞活化与效应过程中起重要作用。
Conclusion (1) The abnormal high expression of peripheral blood co stimulatory molecules CD28 suggested CD28 disorder may play an important role in immuno pathogenesis of CAA.
结论(1)CAA患者外周血共刺激分子CD 2 8异常高表达，提示CD 2 8失调可能在CAA免疫发病中起重要作用。
CD28+T cells, including CD4+CD28+T cells and CD8+CD28+T cells increased significantly in complete remission patients After the efficient treatment with corticosteroid(P<0.01).
激素有效组尿蛋白转阴后CD28分子水平明显上升，且CD4+CD28+T细胞和CD8+CD28+T细胞均较治疗前明显上升，差异有统计学意义（P<0.01）；
Methods The expression of CD28 and CD4 in peripheral blood of 20 healthy persons and 25 patients with UAP was detected by triad colour analytical technique with flow cytometry.
方法运用流式细胞仪三色分析技术检测25例不稳定型心绞痛患者在发病期和缓解期以及20名正常健康对照外周血标本cd 28、CD4的表达。
Objective To explore the changes of CD8 + t cell subtypes especially CD8 + CD28 -t suppressor cells in rats with experimental colitis induced by 2, 4-dinitrofluorobenzene (DNFB).
目的探讨CD 8 +T细胞亚群尤其是CD 8 + CD2 8 - T抑制细胞在2,4二硝基氟苯(DNFB)大鼠实验性结肠炎模型中的变化及其可能作用。
Using anti-CD3 and anti-CD28 to mimic stimulatory signal I / II, to study their function of activing T cells in order to explore the possible mechanism of immune up and down regulation.
利用CD3/28双抗体模拟第一、二信号的变化探讨免疫上下调节的可能机制，为我们研究输血带来的免疫影响及如何纠正提供可依靠的线索。
Using anti-CD3 and anti-CD28 to mimic stimulatory signal I / II, to study their function of activing T cells in order to explore the possible mechanism of immune up and down regulation.
利用CD3/28双抗体模拟第一、二信号的变化探讨免疫上下调节的可能机制，为我们研究输血带来的免疫影响及如何纠正提供可依靠的线索。
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