Actin cleavage by caspase-3 may accelerate proteosome dependent muscle proteolysis.
通过 caspase-3 剪切的Actin可能加速蛋白酶体依赖的肌肉蛋白水解。
In some renal biopsies, immunohistochemical staining for activated caspase 3 was performed.
在一些肾脏活检标本中，免疫组化染色可检测到半胱天冬酶3的表达。
Actin cleavage by caspase-3 may accelerate ubiquitin/proteosome dependent muscle proteolysis (6).
通过caspase-3剪切的Actin可能加速泛素/蛋白酶体依赖的肌肉蛋白水解（6）。
The inflammasomes join together and activate a protein, caspase-1, that in turn triggers an inflammatory response.
这些炎症小体联合起来可以激活半胱天冬酶- 1，这种蛋白依次激活炎症的级联反应。
OBJECTIVE To screen inhibitors of caspase-3, which is a key enzyme responsible for diseases related to cell apoptosis.
目的筛选细胞凋亡相关疾病中重要靶点——卡斯帕酶-3抑制剂。
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the caspase cleavage site in PARP.
该多克隆抗体是采用合成的PARP裂解位点周围残基相对应的肽段免疫动物后制备获得。
Thus, caspase-dependent processing of DBC-1 may act as a feed-forward mechanism to promote apoptosis and possibly also tumor suppression.
因此DBC-1的凋亡蛋白酶依赖的处理过程可能起了促使凋亡的前馈机制的作用，并且也起了肿瘤抑制的作用。
The cortex's immunohistochemistry expression of Bcl-2 was no obvious change(P>0.05). The expression of Caspase-3 decreased obviously(P<0.05).
PNS治疗组大鼠脑皮质Bcl-2表达的阳性细胞数量无明显变化（P＞0.05），Caspase-3表达的阳性细胞数量明显下降（P＜0.05）。
Objective To investigate Caspase-8 expression levels and the relations between Caspase-8 and clinical parameter in human esophagus carcinomas.
目的研究食管癌组织中半胱氨酸蛋白酶8 (Caspase - 8)基因表达及其与临床参数的关系。
AIM: To investigate the spatiotemporal change of caspase-3 at different time in perifocal cortex after focal cerebral ischemia and reperfusion.
目的：观察半胱氨酸蛋白酶3在局灶性脑缺血再灌注不同时间、灶周皮质的动态时空变化。
And almost all humans have lost the caspase 12 gene from their genomes, probably because those who have it are more susceptible to bacterial infections.
大概是由于携带胱冬酶12基因的人更易受细菌感染的侵害，现在几乎所有人都已经失去了该基因。
Objective To clarify the effects of zinc on the proliferation and the expression of caspase-3 in cultured human retinal pigment epithelial (RPE) cells.
目的探讨硫酸锌盐对体外培养的人视网膜色素上皮(retinal pigment epithelium,RPE)细胞增生及Caspase - 3表达的影响。
The DNA contents of spleen and bursa, the ratio of apoptosis and the expression of caspase-3 and Bcl-2 in the spleen and bursa were measured by flow cytometry.
用流式细胞仪检测应激后不同时间脾脏和法氏囊细胞DNA含量、细胞凋亡率以及Caspase - 3和Bcl - 2的表达。
It is concluded that the apoptosis of spleen and bursa cells was obviously affected by heat stress and regulated by the expression of caspase-3 and Bcl-2 protein.
据此说明高温应激能明显影响脾脏和法氏囊细胞凋亡，而这种细胞凋亡的变化受Caspase - 3和Bcl - 2表达的调节。
They revealed that in normal cells, BCL9L helps activate a protein called caspase-2 in response to an abnormal number of chromosomes, triggering a self-destruct sequence.
他们发现在正常的细胞中，BCL9L帮助激活一种叫做半胱天冬酶-2的蛋白质以应对异常数量的染色体，引发自毁程序。
Interrupting the pathway at any point, either by silencing the genes responsible for the inflammasome formation or the gene for caspase-1, resulted in increased cell death.
在任一点阻断这条通路，或者沉默与炎症小体形成相关的基因或者编码半胱天冬酶- 1的基因，都能导致细胞死亡数目增加。
Depending on caspase activation, methadone overcomes doxorubicin resistance, multidrug resistance, and apoptosis resistance in leukemia cells through activation of mitochondria.
依赖于半胱氨酸蛋白酶的激活，美沙酮通过激活线粒体克服了白血病细胞中的阿霉素耐药、多药耐药、和凋亡抑制。
Methods We quantified Caspase-8 expression levels in 96 esophageal cancer issues and their matched normal esophagus tissues by using real-time PCR assay and immunohistochemistry staining.
方法采用实时荧光定量聚合酶链反应和免疫组化染色法检测96例食管癌患者的食管癌组织和癌旁正常组织Caspase-8表达。
AIM: to study the synergistic induction of apoptosis by TRAIL and cisplatin in rhabdomyosarcoma cells and investigate the role of mitochondrial membrane potential and caspase-3 in this process.
目的：探讨肿瘤坏死因子相关诱导凋亡配体(trail)蛋白和顺铂协同抑制横纹肌肉瘤细胞生长和诱导凋亡作用及其机制。
AIM: to study the synergistic induction of apoptosis by TRAIL and cisplatin in rhabdomyosarcoma cells and investigate the role of mitochondrial membrane potential and caspase-3 in this process.
目的：探讨肿瘤坏死因子相关诱导凋亡配体(trail)蛋白和顺铂协同抑制横纹肌肉瘤细胞生长和诱导凋亡作用及其机制。
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