• AIM To study the protective effects of monosialotetrahexosylganglioside (GM1) after hypoxic ischemic brain damage (HIBD) in neonatal rats.

    目的研究外源性单唾液酸四己糖神经节苷脂(GM1)对新生缺氧缺血损伤HIBD)的保护作用

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  • Small fibrin thrombi can form in small arteries of brain, heart, lungs, kidneys, and other organs to produce ischemic tissue damage.

    纤维蛋白血栓心脏以及其它器官的小动脉形成引起组织缺血

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  • Objective to explore the influences of early interventions on learning, memory and neuron apoptosis in the brain of neonatal rats with hypoxic ischemic brain damage (HIBD).

    目的探讨早期干预缺氧缺血性损伤(HIBD)大学习记忆能力神经元凋亡影响

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  • Objective To explore the effect of N-acetylcysteine (NAC) on intercellular adhesion molecule-1(ICAM-1) expression and apoptosis in neonatal rats brain after hypoxic and ischemic brain damage (HIBD).

    目的探讨N-乙酰半胱氨酸NAC缺氧缺血损伤HIBD大鼠脑细胞间黏附分子-1细胞凋亡影响

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  • Through investigating the effect of mild hypothermia on activity of nitric oxide synthase(NOS) in cortical neurons and glycemia levels of neonatal rats with hypoxic ischemic brain damage(HIBD).

    通过低温新生缺氧缺血性脑损伤(HIBD)大脑皮质神经元一氧化氮合酶(NOS血糖水平影响研究,探讨亚低温对缺氧缺血性脑损伤的保护作用机制。

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  • Objective To investigate the changes of blood coagulation state and some prothrombin's function in newborn piglets at different time after hypoxic-ischemic brain damage (HIBD).

    目的研究缺氧缺血新生猪状态以及部分因子促凝活性动态变化,探讨缺氧缺血性脑损伤(HIBD)凝血功能变化。

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  • Objective To study the expression of ICAM 1 at gene transcription level in neonatal rats after hypoxic ischemic brain damage(HIBD).

    目的研究新生动物缺氧缺血性损伤HIBD)后脑细胞间粘附分子-1ICAM- 1)转录水平表达规律。

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  • The pathologic mechanism that hyperglycemia intensified the ischemic brain damage was discussed.

    作者讨论高血糖加剧缺血性损害病理机制

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  • Hypoxia ischemic brain damage (HIBD), which resulted from neonatal asphyxia, is the main cause of death and disability in neonatal periods.

    围产期窒息所致缺氧缺血性损伤(HIBD)新生儿死亡残疾主要原因

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  • Objective To study the changes of plasma PAF levels in neonatal hypoxic ischemic encephalopathy (HIE), and explore the relationship between PAF levels and severity of brain damage.

    目的研究缺氧缺血性脑病(HIE)新生儿血浆血小板活化因子(PAF)水平变化探讨PAF水平HIE损伤程度之间关系。

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  • Objective To develop an improved neonatal piglet model of hypoxic ischemic brain damage (HIBD).

    目的研究新生猪缺氧缺血损伤(HIBD)模型制备。

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  • Hypoxic ischemic (HIE) of newborn is the damage in brain because of perinatal hypoxia or asphyxiation.

    新生儿缺氧缺血性脑病(HIE)指围产期缺氧窒息,导致缺氧缺血性损伤

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  • Objective to study the morphologic changes of mitochondria and metabolic protective effect of fructose 1 6 diphosphate (FDP) intervention in newborn rats with hypoxic ischemic brain damage (HIBD).

    目的探讨16二磷酸果糖(FDP)干预治疗新生缺氧缺血性损伤(HIBD)后脑神经细胞线粒体形态学变化对能量代谢影响

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  • To study the effects of glutathione on hypoxic ischemic brain damage in neonatal rats hippocampal.

    研究谷胱甘肽缺氧缺血损伤引起神经细胞凋亡的作用

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  • Objective To study the protective and therapeutic effect of MK 801 on hypoxic ischemic brain damage.

    目的探讨MK801缺氧缺血性损伤防治作用

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  • Conclusions: Excessive NO produced in brain tissue and insufficient plasma NO participate the course of ischemic brain damage.

    结论脑组织产生过量的NO血浆NO不足参与缺血性损伤过程

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  • Objective To study the role of endogenous carbon monoxide(CO) in newborn rats with hypoxic-ischemic brain damage (HIBD) and the protective effect of Sn-protoporphyrin (SnPP).

    目的探讨内源性一氧化碳CO新生大鼠缺氧缺血性损伤HIBD)中的作用机制及锡原卟保护作用

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  • To explore the pathologic and DNA changes in the brain of the hypoxic ischemic brain damage (HIBD) newborn rats after exposed to high oxygen for long time.

    观察缺氧缺血性损伤(HIBD)新生大鼠时间吸高浓度氧后脑病理学DNA损伤变化

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  • Aim: To study the effects of epicranium medication injection treatment on learning and memory in brain cells of hypoxic-ischemic brain damage (HIBD).

    目的探讨头部药物位点注射缺氧缺血性损伤(HIBD)后学习记忆影响

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  • Objective To observe the change of neuron-specific enolase (NSE) and glial fibrillary acidic protein (GFAP) in neonatal rats' cerebral cortex with hypoxic-ischemic brain damage (HIBD).

    目的了解新生缺氧缺血性损伤(HIBD)时大脑皮质神经元特异性烯醇化酶(nse)胶质纤维酸性蛋白(GFAP)变化

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  • The hypoxic ischemic brain damage (HIBD) seen in survivors with prenatal or postnatal asphyxia is a major cause of disabilities.

    新生儿缺氧缺血性损伤人类致残主要原因之一

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  • GTS-21 ameliorated ischemic brain damage and improved survival.

    GTS - 21可改善局部缺血性脑组织损坏以及提高生存率

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  • Objective To explore the protective effect of Lushi mixture on hypoxic-ischemic brain damage neonatal rats.

    目的探讨鹿石合剂对缺氧缺血损伤新生大鼠保护作用机制。

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  • Ischemic brain damage is a complex process caused by mutiple pathological pathways, which indicates the joint use of the agents may block the cascade by different mechanisms and have better effects.

    缺血性损伤一个复杂病理过程提示只有联合使用作用于不同机制的脑保护剂阻断级联反应可能取得更好疗效。

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  • The findings of preconditioning and ischemic tolerance provide a new idea of prevention on ischemic brain damage.

    预处理缺血耐受发现防治缺血性损伤研究提供思路

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  • Objective To study the neuroprotective effects of lamotrigine (LTG) on hypoxic-ischemic brain damage (HIBD) in neonatal rats, and the influence of administration time and dosage.

    目的研究拉莫三(ltg)缺氧缺血性损伤(HIBD)新生大鼠神经保护作用以及不同用药剂量用药时间作用的影响。

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  • Objective: To study the changes of pathology, ATP production rate and ATP synthase activity in hippocampal cortex of neonatal pigs after hypoxic-ischemic brain damage (HIBD).

    目的研究缺氧缺血性损害新生猪海马皮层病理改变ATP生成、ATP合成酶活性变化。

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  • Objective To investigate the neuroprotective effects of flunarizine (FNZ) and lamotrigine (LTG), and their combination on the hypoxic-ischemic brain damage in fetal rats.

    目的研究桂利嗪(FNZ)、拉莫三(ltg)两药联合给药,对鼠宫内缺血缺氧性损害的保护作用。

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  • Objective to observe the expression of proliferation in hippocampus following hypoxic-ischemic brain damage (HIBD) in neonatal rats and to explore the possible endogenous neurogenesis of brain.

    目的观察新生缺氧缺血性损伤(HIBD)后海马区细胞增殖情况,探讨脑组织内源性修复可能机制。

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  • Conclusion: increase of ET 1 is an important factor leading to ischemic brain damage after SAH. GBE exerts its protective effect by antagonizing pathological increase of ET 1.

    结论SAHET1增加导致缺血性损害重要因素,GBE通过拮抗et 1病理性增多而减轻缺血性脑损害。

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