AIM To study the protective effects of monosialotetrahexosylganglioside (GM1) after hypoxic ischemic brain damage (HIBD) in neonatal rats.
目的研究外源性单唾液酸四己糖神经节苷脂(GM1)对新生鼠缺氧缺血脑损伤(HIBD)的保护作用。
Small fibrin thrombi can form in small arteries of brain, heart, lungs, kidneys, and other organs to produce ischemic tissue damage.
小纤维蛋白血栓可在脑、心脏、肺、肾以及其它器官的小动脉中形成,引起组织缺血。
Objective to explore the influences of early interventions on learning, memory and neuron apoptosis in the brain of neonatal rats with hypoxic ischemic brain damage (HIBD).
目的探讨早期干预对缺氧缺血性脑损伤(HIBD)大鼠学习记忆能力及神经元凋亡的影响。
Objective To explore the effect of N-acetylcysteine (NAC) on intercellular adhesion molecule-1(ICAM-1) expression and apoptosis in neonatal rats brain after hypoxic and ischemic brain damage (HIBD).
目的探讨N-乙酰半胱氨酸(NAC)对缺氧缺血脑损伤(HIBD)大鼠脑细胞间黏附分子-1及细胞凋亡的影响。
Through investigating the effect of mild hypothermia on activity of nitric oxide synthase(NOS) in cortical neurons and glycemia levels of neonatal rats with hypoxic ischemic brain damage(HIBD).
通过亚低温对新生鼠缺氧缺血性脑损伤(HIBD)大脑皮质神经元一氧化氮合酶(NOS)及血糖水平影响的研究,探讨亚低温对缺氧缺血性脑损伤的保护作用机制。
Objective To investigate the changes of blood coagulation state and some prothrombin's function in newborn piglets at different time after hypoxic-ischemic brain damage (HIBD).
目的研究缺氧缺血新生猪凝血状态,以及部分凝血因子促凝活性的动态变化,探讨缺氧缺血性脑损伤(HIBD)时凝血功能变化。
Objective To study the expression of ICAM 1 at gene transcription level in neonatal rats after hypoxic ischemic brain damage(HIBD).
目的研究新生动物缺氧缺血性脑损伤(HIBD)后脑细胞间粘附分子-1(ICAM- 1)在转录水平表达规律。
The pathologic mechanism that hyperglycemia intensified the ischemic brain damage was discussed.
作者讨论了高血糖加剧缺血性脑损害的病理机制。
Hypoxia ischemic brain damage (HIBD), which resulted from neonatal asphyxia, is the main cause of death and disability in neonatal periods.
围产期窒息所致缺氧缺血性脑损伤(HIBD)是新生儿死亡和残疾的主要原因。
Objective To study the changes of plasma PAF levels in neonatal hypoxic ischemic encephalopathy (HIE), and explore the relationship between PAF levels and severity of brain damage.
目的:研究缺氧缺血性脑病(HIE)新生儿血浆血小板活化因子(PAF)水平变化,探讨PAF水平与HIE和脑损伤程度之间的关系。
Objective To develop an improved neonatal piglet model of hypoxic ischemic brain damage (HIBD).
目的研究新生猪缺氧缺血脑损伤(HIBD)模型的制备。
Hypoxic ischemic (HIE) of newborn is the damage in brain because of perinatal hypoxia or asphyxiation.
新生儿缺氧缺血性脑病(HIE)是指围产期缺氧窒息,导致脑的缺氧缺血性损伤。
Objective to study the morphologic changes of mitochondria and metabolic protective effect of fructose 1 6 diphosphate (FDP) intervention in newborn rats with hypoxic ischemic brain damage (HIBD).
目的探讨16二磷酸果糖(FDP)干预治疗新生鼠缺氧缺血性脑损伤(HIBD)后脑神经细胞线粒体形态学变化及对能量代谢的影响。
To study the effects of glutathione on hypoxic ischemic brain damage in neonatal rats hippocampal.
研究谷胱甘肽对缺氧缺血脑损伤引起的神经细胞凋亡的作用。
Objective To study the protective and therapeutic effect of MK 801 on hypoxic ischemic brain damage.
目的探讨MK801对缺氧缺血性脑损伤的防治作用。
Conclusions: Excessive NO produced in brain tissue and insufficient plasma NO participate the course of ischemic brain damage.
结论:脑组织产生过量的NO和血浆NO的不足参与了缺血性脑损伤的过程。
Objective To study the role of endogenous carbon monoxide(CO) in newborn rats with hypoxic-ischemic brain damage (HIBD) and the protective effect of Sn-protoporphyrin (SnPP).
目的探讨内源性一氧化碳(CO)在新生大鼠缺氧缺血性脑损伤(HIBD)中的作用机制及锡原卟啉的保护作用。
To explore the pathologic and DNA changes in the brain of the hypoxic ischemic brain damage (HIBD) newborn rats after exposed to high oxygen for long time.
观察缺氧缺血性脑损伤(HIBD)新生大鼠长时间吸高浓度氧后脑病理学及DNA损伤的变化。
Aim: To study the effects of epicranium medication injection treatment on learning and memory in brain cells of hypoxic-ischemic brain damage (HIBD).
目的:探讨头部药物位点注射对缺氧缺血性脑损伤(HIBD)后学习和记忆的影响。
Objective To observe the change of neuron-specific enolase (NSE) and glial fibrillary acidic protein (GFAP) in neonatal rats' cerebral cortex with hypoxic-ischemic brain damage (HIBD).
目的了解新生鼠缺氧缺血性脑损伤(HIBD)时大脑皮质神经元特异性烯醇化酶(nse)和胶质纤维酸性蛋白(GFAP)的变化。
The hypoxic ischemic brain damage (HIBD) seen in survivors with prenatal or postnatal asphyxia is a major cause of disabilities.
新生儿缺氧缺血性脑损伤是人类致残的主要原因之一。
GTS-21 ameliorated ischemic brain damage and improved survival.
GTS - 21可改善局部缺血性脑组织损坏以及提高生存率。
Objective To explore the protective effect of Lushi mixture on hypoxic-ischemic brain damage neonatal rats.
目的探讨鹿石合剂对缺氧缺血脑损伤新生大鼠保护作用的机制。
Ischemic brain damage is a complex process caused by mutiple pathological pathways, which indicates the joint use of the agents may block the cascade by different mechanisms and have better effects.
缺血性脑损伤是一个复杂的病理过程,提示只有联合使用作用于不同机制的脑保护剂,阻断其级联反应才可能取得更好疗效。
The findings of preconditioning and ischemic tolerance provide a new idea of prevention on ischemic brain damage.
预处理和缺血耐受的发现为防治缺血性脑损伤的研究提供了新思路。
Objective To study the neuroprotective effects of lamotrigine (LTG) on hypoxic-ischemic brain damage (HIBD) in neonatal rats, and the influence of administration time and dosage.
目的研究拉莫三嗪(ltg)对缺氧缺血性脑损伤(HIBD)新生大鼠的神经保护作用,以及不同用药剂量和用药时间对该作用的影响。
Objective: To study the changes of pathology, ATP production rate and ATP synthase activity in hippocampal cortex of neonatal pigs after hypoxic-ischemic brain damage (HIBD).
目的:研究缺氧缺血性脑损害新生猪海马皮层病理改变及ATP生成率、ATP合成酶活性变化。
Objective To investigate the neuroprotective effects of flunarizine (FNZ) and lamotrigine (LTG), and their combination on the hypoxic-ischemic brain damage in fetal rats.
目的研究氟桂利嗪(FNZ)、拉莫三嗪(ltg)及两药联合经孕鼠给药,对胎鼠宫内缺血缺氧性脑损害的保护作用。
Objective to observe the expression of proliferation in hippocampus following hypoxic-ischemic brain damage (HIBD) in neonatal rats and to explore the possible endogenous neurogenesis of brain.
目的:观察新生大鼠缺氧缺血性脑损伤(HIBD)后海马区细胞增殖的情况,探讨脑组织内源性修复的可能机制。
Conclusion: increase of ET 1 is an important factor leading to ischemic brain damage after SAH. GBE exerts its protective effect by antagonizing pathological increase of ET 1.
结论:SAH时ET1增加是导致缺血性脑损害的重要因素,GBE通过拮抗et 1病理性增多而减轻缺血性脑损害。
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