Methods A549 cells cultured in vitro were divided into heat stress group and BPDE group.
方法体外培养的A549细胞分为高温应激组和BPDE组。
The HPLC method established in this study was applied to measure BPDE-DNA adducts, and found it was simple, time-saving and low-cost.
本实验建立的HPLC检测DNA加合物的方法具有简单快速、操作简便、成本低廉等特点。
The measurement of BaP, BaP metabolite and acid-hydrolysis products of DNA adducts by HPLC indicated that there were BPDE-DNA adducts.
同时用HPLC检测反应体系中的苯并（a）芘含量、苯并（a）芘代谢物及DNA加合物酸水解后的产物。
Conclusions Anti-BPDE can result in DNA strand breakage, and the degrees of damage is related to the administrated doses of anti BPDE.
结论反式BPDE可导致DNA断裂损伤，其损伤程度与剂量有一定关系。
Conclusions Anti-BPDE can result in DNA strand breakage, and the degrees of damage is related to the administrated doses of anti BPDE.
结论反式BPDE可导致DNA断裂损伤，其损伤程度与剂量有一定关系。
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