The M domain, which encodes the DNA-binding domain and plays the roles of both binding DNA and forming dimmers, is the most conserved region.
其中M区高度保守,它编码真核生物转录因子的DNA结合域,具有DNA结合和二聚体形成的作用。
The M domain, which encodes the DNA-binding sequence and plays the roles of both binding DNA and forming dimmers, is the most conserved region.
其中M区高度保守,它编码真核生物转录因子的DNA结合域,具有DNA结合和二聚体形成的作用。
The compounds show absorption hypochromicity, fluorescence enhancement, DNA melting increasement when binding to CT·DNA.
结果显示,混配配合物与DNA 作用时,使紫外吸收明显减色,荧光显著增强,DNA熔点升高。
The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).
这两种酶是组蛋白乙酰转移酶(它能给蛋白质添加乙酰基)和甲基化dna结合蛋白- 2(它能把DNA上的甲基去除)。
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).
EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子,它可以EGR响应元素(ER),调节靶基因的表达(1)。
CREB DNA binding activity of tested animals at different developing time was higher than that in control groups.
实验组大鼠幼仔小脑CREBDNA结合活性均高于相应对照组。
AIM to explore the changes in the activation of signal transducer and activator of transcription-3 STAT3 and DNA binding activation in facial nerve nucleus after facial nerve injury and repair.
目的:探讨面神经损伤与修复条件下,面神经核运动神经元信号转导子和转录激活子3的活性以及DNA结合活性的变化。
The function role of mitochondrial transcription termination factor is binding mitochondrial special DNA and leading to terminate mitochondrial gene transcription.
线粒体转录终止因子蛋白的作用是与线粒体dna的特异位点结合,导致线粒体基因转录停止。
Telomeric binding proteins protect telomeric DNA while telomeric associated proteins have effect on telomere through interaction with telomeric binding proteins.
端粒结合蛋白直接保护端粒DNA,端粒相关蛋白通过与端粒结合蛋白的相互作用间接影响端粒的功能。
This score enables ranking of different DNA binding sites given a protein binding site and vice versa and can be used in molecular design protocols.
这评分使排名不同的DNA结合位点提供的蛋白质结合位点,反之亦然,可以用于分子设计议定书。
The phosphorylation of STAT5 and its location were examined by double immunohistochemical staining and the binding of STAT5 with DNA was determined by electrophoretic mobility shift assay (EMSA).
用双染免疫组化法检查脾细胞中STAT 5磷酸化与STAT 5抗原的定位。用电泳迁移率变动分析(EMSA)测定STAT 5与DNA探针的结合力。
Methods: DNA damage was measured by the loss of fluorescence after DNA binding to ethidium bromide and by the increased DNA mobility in agarose gel electrophoresis.
方法:通过DNA结合溴乙锭后的荧光损失和DNA琼脂糖凝胶电泳的迁移率来测定dna的损伤程度。
No open reading frame encoding TNP1/TNPA-like DNA binding protein were found in this element.
该因子没有能够编码类似TNP1/TNPA的DNA结合蛋白的开读框。
The yeast three-hybrid have three components: a protein fused with DNA binding domain, a hybrid RNA molecule, a protein fused with DNA activation domain.
酵母三杂交系统由三部分组成:DNA结合结构域融合蛋白、杂交RNA分子、DNA激活结构域融合蛋白。
Novel IFN receptor 1 binding proteins, DNA encoding them, and methods of modulating cellular response to interferons.
新型IFN受体1结合蛋白质,编码它们的DNA,以及调节细胞对干扰素的反应的方法。
Novel IFN receptor 1 binding proteins, DNA encoding them, and method of modulating cellular response to interferons.
新型IFN受体1结合蛋白质,编码它们的DNA,以及调节细胞对干扰素的反应的方法。
Objective To develop a high throughput method of screening the binding site of DNA adducts.
目的探讨建立一种高通量的筛选DNA加合物结合位点的方法。
Recent studies have highlighted the complementarity of DNA sequence and shape in modeling TF binding in vitro.
最近的研究强调了互补的DNA序列和形状建模TF结合体外。
Objective: To observe whether there exist non nuclear DNA binding proteins in rats skeletal muscle sarcoplasmic reticulum.
目的:观察大鼠骨骼肌肌质网上是否存在非核dna结合蛋白。
Conclusion The AP-1 DNA binding ability was markedly increased in liver in burned mice.
结论烧伤早期引起小鼠肝组织AP - 1的DNA结合活性显著增强。
Telomeric proteins is composed of double DNA binding protein, single DNA binding protein and telomeric associated proteins.
端粒蛋白包括端粒双链dna结合蛋白、端粒单链dna结合蛋白、其它端粒相关蛋白。
To improve a gel retardation Assay for the study of binding in the nuclear protein and DNA.
目的:探讨改良的凝胶阻滞法用于核蛋白-DNA结合的检测。
This research will facilitate to find new DNA-binding protein, and it is important to reveal the molecular mechanisms of DNA replication and transcription and DNA repair and recombination.
该研究对于寻找新的DNA结合蛋白,研究生物体中遗传信息的复制、转录、修复和重组的分子生物学机制具有重要意义。
DNA binding domains that are elongated, with a shape that is somewhat like a finger. The shape of the domain is coordinated by one or more zinc atoms.
伸展的、形状有些像手指的DNA结合域。这一形状由一个或多个锌原子进行协调。
By using absorption spectra method and EB as a fluorescence probe, we studied the action modes of the complexes binding to DNA.
用紫外吸收光谱法、荧光光谱法(EB为探针)详细研究了镍、锰、锌与DNA的作用方式。
Conclusion: Pazufloxacin interacts with CT-DNA in the mode of groove binding.
结论:帕珠沙星以沟槽键合方式与DNA相互作用。
HSF is present in a latent state under normal conditions; it is activated upon heat stress by induction of trimerization, high affinity binding to DNA and transcriptional activity.
在正常生长条件下,热激因子处于钝化的单体状态,而当热激时,热激因子形成三聚体并与DNA结合,同时通过转录激活域的活化而激活热激基因的表达。
Methods: receptor radioligand binding assay, receptor DNA binding assay and immunofluorescence methods were used.
方法:采用受体放射配基结合分析、受体-DNA结合分析及免疫荧光技术。
Methods: receptor radioligand binding assay, receptor DNA binding assay and immunofluorescence methods were used.
方法:采用受体放射配基结合分析、受体-DNA结合分析及免疫荧光技术。
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