This mini-review mentions web sites that are useful in structure-based drug design.
这个小综述提到了对基于结构的药物设计有用的网站。
Rational drug design (also known as structure-based drug design) uses the high-resolution (atomic) structure of the target molecule, and of molecules that bind to it.
合理化药物设计利用靶分子和其结合分子的高分辩率结构。
BACKGROUND: the protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease.
背景:疾病相关蛋白质的蛋白质结构对进行抗一种特定疾病的基于结构的药物设计是重要的。
By employing a combination of structure-based drug design and high-throughput screening approaches, several useful compounds for treating HCV infections have been successfully introduced.
通过基于分子结构的药物设计与高效筛选技术,以及免疫疗法的研究进展,已有若干药物可有效的治疗丙肝。
Based on the experience in designing drug refining workshop, the key points in design process and the experience of selecting important equipment were summarized in this article.
根据药物精制车间的设计实践,归纳其关键设计要点及主要设备选择的经验。
Structure-based drug molecule design and organic synthesis; Chemical biology.
药物小分子合成;计算机辅助药物设计;化学生物学。
Drug design is based on the mechanisms of the drug and target interaction to achieve optimization of the leads.
当代药物设计是通过阐明药物与靶标相互作用的机理,对药物先导化合物进行改造和优化。
Computer-aided molecular design (CAMD) is now an uprising subject in medicinal chemistry among which structure-based rational drug design is attracting more and more attention.
计算机辅助药物分子设计近年来已成为新药创制的重要手段。 基于结构的合理药物分子设计则是多学科交互融合和渗透的体现。
The rational drug design is based on the detailed knowledge of the action mechanism.
合理进行药物分子设计的前提是对药物—靶分子作用机制有深入的了解。
This article reviews the drug target's discovery, drug design based on targets, as well as prospects in developing novel drug.
该文综述了药物靶标的发现、基于靶标的药物设计及其在新药研究中的应用前景。
OBJECTIVE:To design Army No. 1-based utility program for the extension of drug control in the interest of statistic analysis of drug control.
目的依托“军卫一号”工程,设计扩展药品管理系统应用程序,用于药品管理综合统计分析。
OBJECTIVE:To design Army No. 1-based utility program for the extension of drug control in the interest of statistic analysis of drug control.
目的依托“军卫一号”工程,设计扩展药品管理系统应用程序,用于药品管理综合统计分析。
应用推荐