• Azole derivatives, their use, production and usage.

    唑类衍生物,其用途,生产和使用。

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  • The invention relates to a multi-effect azole suspending agent and a method for preparing the same.

    本发明涉及一种多效唑悬浮剂及其制备方法。

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  • The azole antifungals, widely prescribed prophylactically, are known to have many drug2013drug interactions.

    处方中经常使用的三唑类抗真菌制剂已知有许多药物相互作用。

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  • Other azole antifungals such as itraconazole are substantially more expensive and do not have greater efficacy.

    其他的吡咯类抗真菌药如伊曲康唑更加昂贵,且并不会有更好的效果。

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  • Conventional diagnosis of aspergillosis is limited by poor culture yield, and so the true frequency of azole resistance has been unclear.

    常规曲霉病诊断方法由于培养能力限制,不能准确测定对唑类药物的耐药水平。

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  • Management of breakthrough invasive aspergillosis in the context of mould-active azole prophylaxis is not defined by clinical trial data.

    在现行的唑类药物预防的模式背景下,没有通过临床实验资料定义侵袭性曲菌病的突破性治疗。

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  • Azole and triazole drugs are cytochrome P450 inhibitors widely used as fungal antibiotics and possessing potent antimycobacterial activity.

    唑类和三氮唑类药物作为细胞色素P 450抑制剂广泛被作为抗真菌药物和抗微生物药物使用。

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  • The present invention provides oral pharmaceutical formulation for azole antimicrobial drugs such as itraconazole, saperconazole, ketoconazole, and fluconazole.

    本发明提供吡咯抗微生物药物诸如伊曲康唑、沙康唑、酮康唑和氟 康唑的口服药物制剂。

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  • It is an object of the present invention to provide a pharmaceutical composition containing a stable azole-based compound, which is useful as an antifungal agent.

    本发明提供一种含有作为抗真菌药有用且稳定的吡咯类化合物的药物组合物。

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  • We present here the crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121 in complex with the triazole drug fluconazole, revealing a new azole heme ligation mode.

    我们提出了肺结核分支杆菌细胞色素P 450CYP121与三氮唑类药物氟康唑的复合物的晶体结构,揭示了唑类与亚铁血红素新的结合模式。

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  • We present here the crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121 in complex with the triazole drug fluconazole, revealing a new azole heme ligation mode.

    我们提出了肺结核分支杆菌细胞色素P 450CYP121与三氮唑类药物氟康唑的复合物的晶体结构,揭示了唑类与亚铁血红素新的结合模式。

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