APL patients were treated with ATRA for induction remission.
A TRA诱导缓解治疗急性早幼粒细胞白血病202例。
In addition, many researches show that ATRA can inhibit the proliferation of SMC.
另外，国内外研究显示：维甲酸对血管平滑肌细胞的增生有明显的抑制作用。
Conclusion: JNKphosphorylating mediated ATRA inhibition of apoptosis in Y79 cells.
结论：ATRA可抑制Y 79细胞生长，其过程是由磷酸化的JNK介导。
Conclusion There are significant improvement in prognosis of APL treated with ATRA.
结论全反式维甲酸对急性早幼粒细胞性白血病患者的预后有很大改善。
Trypan blue exclusion was used to detect the antiproliferative effect of ATRA on SY5Y cells.
采用台盼蓝拒染法检测ATRA对SY5Y细胞的体外抗增殖作用；
Objective to study the mechanism of drug resistance of APL to ATRA and the methods of reversion.
目的揭示急性早幼粒细胞白血病产生维甲酸耐药的机制，探讨耐药性逆转的方法。
These results suggested that ATRA might have clinical application for treatment of retinoblastoma.
提示，ATRA可能是一种潜在的抗视网膜母细胞瘤治疗药物。
BSSXG combined with ATRA is effective to treat MDS-RA, and worthy of further study and development.
补髓生血颗粒为主配合小剂量atra是治疗MDS - RA的有效方法，值得在临床上推广和进一步深入研究。
F. atra was omnivorous. The food list was mainly made up of vegetations, but also contained some animals.
骨顶鸡是杂食性鸟类，食物以植物为主，但也摄取动物性食物。
METHODS CTX-dwas fractionated and purified from Naja naja atra venom by column chromatography and RP-HPLC.
方法应用柱层析及RP- HPLC，从眼镜蛇毒粗毒中分离纯化细胞素素（CTX）。
Objective To investigate the protective effect of all-trans retinoic acid (ATRA) on podocyte lesion in diabetic rats.
目的探讨全反式维甲酸（ATRA）对糖尿病大鼠足细胞损伤的保护作用。
Results There were obvious differences in gene expression between human lung cancer cells before and after ATRA treatment.
结果在全反式维甲酸诱导前后的细胞之间存在明显的基因表达差异。
ATRA could induce morphological differentiation and inhibit growth of SY5Y cells and showed time and dose dependent manner.
ATRA对SY5Y细胞有抗增殖作用和诱导细胞分化作用，并呈一定时间和剂量依赖关系。
Results Different concentrations of ATRA have different effects on morphology, proliferation and apoptosis of the RPE cells.
结果不同浓度的ATRA对RPE细胞的形态、增殖有 不同的影响。
Conclusion the combination of ATRA with bufalin can significantly enhance the differentiation of NB4 cells in vitro culture by ATRA.
结论：蟾蜍灵抑制nb 4细胞活力及诱导细胞发生凋亡，蟾蜍灵与atra联合应用可显著增强A TRA对NB 4细胞的诱导分化作用。
All-Trans Retinoic Acid (ATRA) is an antiproliferative drug against tumor and magnetic nanoparticles is a drug for tumor hyperthermia.
全反式维甲酸(atra)是一种用于肿瘤治疗的抗增殖药物，磁性纳米颗粒则是一种可用于肿瘤热疗的药物。
It is concluded that JWA may play double important roles in regulating ATRA and TPA-induced differentiation and apoptosis in leukemic cells.
结论：JWA基因在实现ATRA及TPA诱导白血病细胞分化和凋亡中可能具有双重调节作用；
Mehtods: Using cell observation and MTT method, to study the phenomena that proliferation of LS174T and CW-2 cell strain were inhibited by ATRA.
方法：应用细胞观察和MTT方法，研究ATRA对结肠癌不同增殖能力细胞株LS174T和CW - 2细胞的生长抑制现象。
Conclusions ATRA can decrease the excretion of urinary podocyte and proteinuria. ATRA has a protective effect on podocyte lesion in diabetic rats.
结论ATRA可以减少糖尿病大鼠尿足细胞的排泄、降低尿蛋白，对肾脏足细胞损伤具有保护作用。
Objective To investigate the possible pathway of the effect of all-trans retinoic acid(ATRA) on the apoptosis of human breast cancer cell line(MCF-7).
目的：探讨全反式维甲酸（ATRA）对人乳腺癌MCF-7细胞凋亡的影响及作用途径。
Conclusion ATRA and Kanglaite injection can reverse precancerous squamous epithelial lesions in rabbits and may be used as new intervention chemicals.
结论全反式维甲酸和康莱特注射液可逆转家兔颊黏膜鳞状上皮癌前病变，有可能成为新的化学阻断干预药物。
Methods Improved PCR-based subtractive hybridization was used to clone the genes from apoptotic prostatic carcinoma cell line DU-145 cells induced by ATRA.
方法：应用全反式维甲酸诱导前列腺癌DU 145细胞凋亡，建立细胞凋亡模型，采用基于PCR的改良消减杂交技术克隆与凋亡相关的基因。
Results: ICA could inhibit the telomerase activity and induce the differentiation and restrain the proliferation of HL-60 cells. The effect was promoted by ATRA.
结果：ICA可明显抑制端粒酶活性，对白血病细胞均有较明显的诱导分化和抑制增殖作用，且与A TRA合用可产生明显的协同效应。
Conclusion ATRA treatment can affect serum level of TNF or IL-6 in patients with APL, but neither TNF nor IL-6 has linear correlation with the variation of WBC number.
结论全反式维甲酸治疗虽然影响APL患者血清tnf和IL - 6水平，但与该组患者的外周血wBC数量变化无线性关系。
Conclusion ATRA plays an important role in regulating the differentiation-related gene expression. ATRA-induced differentiation is a complex process with multiple genes involved.
结论全反式维甲酸具有调控分化相关基因表达与否的重要作用，由RA诱导的肿瘤细胞再分化是一个多基因参与的过程。
ConclusionATRA could inhibit proliferation of yolk sac tumor cell line, and down regulation of VEGF could be the inhibitory mechanism of ATRA on yolk sac tumor cell line in vitro.
结论全反式维甲酸可以抑制睾丸卵黄囊瘤细胞的增殖，抑制肿瘤增殖机制可能与下调VEGF的表达有关。
CONCLUSION: ATRA cannot induce HL 60 to achieve terminal differentiation, but the differentiation of HL 60 can be induced by ATRA and the differentiated leukemia cells are easy to apoptosis.
结论：ATRA并不能诱导HL-60细胞完成终端分化，但是该药可以诱导白血病细胞向成熟方向分化，而且已分化的肿瘤细胞于发生凋亡。
Objective: To explore the mechanism of prevention and therapy by retinoic acid in cancer and isolate ATRA-target gene and explore the mechanism of expression regulation of mitochondrial gene.
目的：探讨维甲酸在预防和治疗肿瘤中的作用机制，分离受维甲酸调控的靶基因。
Objective To clone the apoptosis-related genes induced by all trans-retinoic acid(ATRA) from prostatic carcinoma cell line DU-145, and investigate the molecular mechanism of the apoptotic process.
目的：克隆全反式维甲酸诱导前列腺癌细胞系DU 145细胞产生凋亡的相关基因。
Objective To clone the apoptosis-related genes induced by all trans-retinoic acid(ATRA) from prostatic carcinoma cell line DU-145, and investigate the molecular mechanism of the apoptotic process.
目的：克隆全反式维甲酸诱导前列腺癌细胞系DU 145细胞产生凋亡的相关基因。
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