The effects were blocked by AT1 receptor antagonist.
AT1受体拮抗剂可以完全阻断其作用。
Objective to summarize the application and research of telmisartan-new style AT1 receptor antagonists.
目的综述新型AT 1受体拮抗剂替米沙坦的应用与研究概况。
To investigate the effects of Valsartan on the positive AT1 receptor in patients cardiac failure with the diabetes mellitus and hypertension.
观察抗AT1受体自身抗体阳性的糖尿病合并高血压心功能不全患者缬沙坦靶向治疗对心功能的疗效。
Objective To investigate the genetic polymorphism of sartan drug metabolic enzyme CYP2C9 and angiotensin AT1 receptor in hypertensive patients.
目的本研究旨在观察沙坦类药物代谢酶CYP2C9和反应受体AT1的遗传多态性在高血压患者中的分布特征。
CONCLUSION: the results suggest that Cys 289 and Gln 257 play important roles in the activation of AT1 receptor induced by mechanical stresses.
结论：结果提示AT 1受体上位于257位的谷氨酰胺和289位的胱氨酸在机械牵张引起的AT 1受体激活中起了重要作用。
Do you think insulin resistance plays a major role in this effect? And what is the role of the AT1 receptor selectivity of valsartan in this effect?
胰岛素抵抗以及缬沙坦作为选择性at 1受体阻断剂，在这种作用机制中起什么作用呢？
AIM: To study the effect of candesartan cilexetil (candesartan), a new AT1 receptor antagonist, on sinoaortic denervation (SAD)-induced cardiovascular hypertrophy and its potential mechanisms in rats.
目的：研究新型AT_1受体拮抗剂坎替沙坦对大鼠去窦弓神经（SAD）引起的心血管肥大的作用及其可能机制。
AIM: To study the effect of candesartan cilexetil (candesartan), a new AT1 receptor antagonist, on sinoaortic denervation (SAD)-induced cardiovascular hypertrophy and its potential mechanisms in rats.
目的：研究新型AT_1受体拮抗剂坎替沙坦对大鼠去窦弓神经（SAD）引起的心血管肥大的作用及其可能机制。
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