In vivo phosphorylation at Ser315 has been observed following UV-irradiation, and a Ser315Ala mutant p53 has reduced activity as a transcription factor (17).
紫外辐射后第315位丝氨酸发生在体磷酸化已被观察到，而且Ser315Ala突变的p53能够减少其作为转录因子的活性（17）。
Sadly, changing ways of life, such as reduced physical activity, are making people unhealthier and, in turn, prone to such diseases as cancer.
可悲的是，生活方式的改变，例如减少身体活动，正在使人们丧失健康并从而易于发生癌症等疾病。
Sadly, changing ways of life, such as reduced physical activity, are making people unhealthier and, in turn, prone to such diseases as cancer.
可悲的是，生活方式的改变，例如减少身体活动，正在使人们丧失健康并从而易于发生癌症等疾病。
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