Conclusion Mutation of Exon a in ar gene plays an important part in infertile men with oligospermia.
结论雄性激素受体基因外显子A即基因转录激活区的突变是造成少精不育的重要原因。
Conclusion: Mutation of Exon a in ar gene plays a very important part in development of infertile men with oligospermia.
结论:雄性激素受体基因外显子a即基因转录激活区的突变是造成少精不育的重要原因。
Methods PCR and DNA sequencing were performed to study the AR gene mutation; Mbo I restriction endonuclease was used to detect existence of the mutation in normal controls;
并对发现突变的基因进行分析。方法应用PCR扩增、DNA序列测定等技术分析所有AR基因外显子及其邻近DNA序列片段;
Conclusions Androgen receptor gene CAG length showed polymorphism in older men, most of the CAG length focused on 21-24. This study offered the basic data on relationship for AR gene and disease.
结论自然人群中老年男性雄激素受体基因CAG重复序列呈现多态性,多数集中在21 - 24,为进一步研究AR基因变异与疾病的关系提供依据。
Objective to determine the gene regulation of androgen receptor (AR).
目的:研究雄激素受体(AR)的基因调控。
The AR) reporter gene assay is useful in screening androgenic effect of chemicals.
本研究建立的AR报告基因试验可作为化学物雄激素活性筛选的理想方法。
To develop an androgen receptor (AR) reporter gene assay in which the reporter gene is chloramphenicol acetyltransferase (CAT).
建立以氯霉素乙酰化酶(CAT)为报告基因的雄激素受体(AR)报告基因试验。
Objective:To investigate the relationship between the polymorphic CAG short-tandem repeat(STR) at the androgen receptor(AR) gene exon 1 and lung cancer.
目的:探讨人雄激素受体(AR)基因第一外显子CAG串联短重复序列(STR)多态性与肺癌发生之间的关系。
In in vitro, DHT increased the AR activity and induced the expression of luciferase reporter gene in a concentration-dependent manner.
核净未能引起荧光素酶活性值的增加,但菌核净能抑制DHT依赖的AR活性,并呈现。
Objectives To study the relation between the expression of recombination activating gene-1 (RAG1) and the differentiation of T help cell in allergic rhinitis (AR);
目的探讨在变应性鼻炎(AR)发病机理中重组激活基因—1(RAG1)的表达和T辅助淋巴细胞趋向性分化之间的关系;
Objectives To study the relation between the expression of recombination activating gene-1 (RAG1) and the differentiation of T help cell in allergic rhinitis (AR);
目的探讨在变应性鼻炎(AR)发病机理中重组激活基因—1(RAG1)的表达和T辅助淋巴细胞趋向性分化之间的关系;
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