AIM: to investigate the apoptotic pathway of MCF-7 breast cancer induced by the grub extract in vitro.
目的：研究蛴螬提取物对MCF - 7人乳腺癌细胞株凋亡通路的影响，为天然药物蛴螬的开发提供实验和理论依据。
The most important of these pathways are the signal transduction pathway, the cell-cycle control pathway, the apoptotic pathway, and the angiogenesis-metastasis route.
其中最重要的包括信号转导、细胞周期调控，凋亡以及血管生成-肿瘤转移。
Conclusions - Our study identifies a novel cardiac apoptotic pathway in which ARC is dephosphorylated by calcineurin. This pathway could be a component in the cardiac apoptotic machinery.
结论—我们的研究发现了一条新的心脏凋亡通路，其中钙神经素使ARC发生去磷酸化反应诱导凋亡的发生。这条通路可能成为心脏凋亡机制中的组成部分。
Conclusions - Our study identifies a novel cardiac apoptotic pathway in which ARC is dephosphorylated by calcineurin. This pathway could be a component in the cardiac apoptotic machinery.
结论—我们的研究发现了一条新的心脏凋亡通路，其中钙神经素使ARC发生去磷酸化反应诱导凋亡的发生。这条通路可能成为心脏凋亡机制中的组成部分。
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