More specifically, the present invention relates to the tumor-associated antigen binding protein designated RS7, and other EGP-1 binding-proteins.
更具体地，本发明涉及名为rs7的肿瘤相关抗原结合蛋白和其它EGP - 1结合蛋白。
The invention further relates to humanized, human and chimeric RS7 antigen binding proteins, and the use of such binding proteins in diagnosis and therapy.
本发明还涉及人源化，人和嵌合RS7抗原结合蛋白，以及该结合蛋白在诊断和治疗中的用途。
Specific antibody was screened by 3 rounds of panning of phage antibody library with the fusion protein. The antigen binding activity and DNA sequences of positive clones were determined and analyzed.
以该融合蛋白为固相抗原，对噬菌体抗体库进行3轮淘筛，并对所获阳性克隆进行抗原结合活性测定和DNA序列测定。
The substitutions of amino acid tended to gather around the putative antigen-binding sites.
氨基酸的替换趋于集中在假定的抗原结合位点附近。
An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof.
本发明的抗体可以是全长抗体或其抗原结合部 分。
An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof.
本发明的抗体可以是全长抗体或其抗原结合部 分。
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